著者

山岡 桂子 近森 温子 阿部 由明 所 安夫

出版者

一般社団法人 日本医療薬学会

雑誌

病院薬学 (ISSN:03899098)

巻号頁・発行日

vol.2, no.2, pp.111-116, 1976 (Released:2011-08-11)

参考文献数

2

被引用文献数

1

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The number of glass particles arising in parenteral solution upon cutting of ampules was determined with use of 5-ml transparent and brown ampules. Cutting by “cracking” produced most satisfactory results of all methods devised. It was found as a result of the investigation by X-ray fluoroscopy that the solution contained in the ampules was almost completely free from particles from a file used for cutting. Mice injected intravenously into the tail with large amount of glass particles from ampule died of shock due to multiple pulmonary thrombosis. Tubercles caused by glass particles were observed in mice which survived the experiment without acute symptoms.