著者

小此木 丘 星 昭二 本間 学 須藤 謙三郎 飯塚 久義 佐藤 信

出版者

The Kitakanto Medical Society

雑誌

北関東医学 (ISSN:00231908)

巻号頁・発行日

vol.12, no.3, pp.199-207, 1962 (Released:2009-11-11)

参考文献数

15

被引用文献数

2 1

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An injection of Habu-snake venom, heated for 10 minutes at 100°C., caused myolysis at the site, histologically. But different from crude venom action, no hemorrhagic changes were recognized. At first, disappearance of mitchondria in the muscular fibers was seen, and then muscular splitting and lysis followed.While the myolytic changes caused by crude venom began immediately af ter the injection, the beginning of the changes were delayed when the heated material were used.Anti-Habu-serum neutralised the toxicity of the heated venom, and also, E.D.T.A.-Ca, Cocarboxylase and α-Thiolactoylglicine-Na repressed the toxicity in vitro.