著者

飯田 信保

出版者

The Kitakanto Medical Society

雑誌

北関東医学 (ISSN:00231908)

巻号頁・発行日

vol.10, no.1, pp.92-115, 1960 (Released:2010-02-17)

参考文献数

18

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最近のめざましい学童生徒の身体発育に伴ない, その性的発育は学校保健はもとより社会的にも一つの関心事であることはいうまでもない.けれども性器自体の発育評価は実際に特殊な標本による以外は行なうことができない.さきに著者は辻等と共同にて健康優良児について第2次性徴である乳房, 腋毛等の発育を観察報告した.これらは早熟児が多く含まれる関係上, 一般小学校児童についての性熟の指標とすることはできないので, この方面の研究を行なう必要に迫られた.この目的で乳房を中心とする青春前期の発育とこれに影響し或は関聯ありと推定される因子について計測を実施したのでその成績を報告する.

著者

二宮 俊作

出版者

The Kitakanto Medical Society

雑誌

北関東医学 (ISSN:00231908)

巻号頁・発行日

vol.10, no.4, pp.594-614, 1960-07-01 (Released:2009-10-21)

参考文献数

10

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Fifty four newborns, 659 female and 774 male sucklings with mormal hip joints, and 220 female and 40 male sucklings with congenital hip dislocation were investigated for the skincrease on the medial side of the thigh, with the following results : 1) This crease is produced in the foetus by adducting force, exerted on the flexion of the hip and knee joint, and disappears in about 2 years after birth. This is dfferent from other skin-creases in this respect, and therefore can adequately be named “forced skincrease”.2) The skin-crease which is found under inguinal groove nearly in parallel with it disappears relatively early.3) Symmetry or asymmetry of these creases respectively found on the two thighs can not have any diagnostic significance.4) When the skin-creases respsctively found on the both thighs are asymmetry under the inguinal grooves, or when they are asymmetry, being respectively found a little higher and lower than the middle parts of the thighs, or when they are asymmetry, two being found slightly above and below the middle part of one thigh, and one on the middle part of the other thigh, there is strong suspicion of dislocation.

著者

宮崎 有紀子 佐藤 由美 大野 絢子

出版者

The Kitakanto Medical Society

雑誌

北関東医学 (ISSN:13432826)

巻号頁・発行日

vol.52, no.4, pp.261-266, 2002-07-01 (Released:2009-10-21)

参考文献数

16

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【背景・目的】室内環境の清潔保持は, 健康な生活を営むために重要である.その方策を立てるため, 室内の塵埃量やダニ抗原量の季節変動, 床材の種類とコナダニ(ダニ)数, 適切な塵埃除去等を検討した.【対象と方法】室内の塵埃量とダニ抗原量の測定は, 電気掃除機及びACAREX testによって行い, 塵埃中のダニ数測定は実体顕微鏡によって行った.【結果】室内塵埃量は冬季から春季にかけて増加し, 塵埃中のダニ抗原量は秋期に増加した.ダニは絨毯敷き詰めの部屋に多くみられ, 板敷きでも清掃しない部屋には多かった.電気掃除機による塵埃除去効率は, 床材の種類で大きく異なり, また掃除機の使用法が塵埃除去効率をあげるために重要と思われた.【結語】室内の清潔を保つためには, 塵埃やダニ抗原量を減らすことが重要である.今回得られたデータを活用した環境整備マニュアルを作成し, 学生や地域住民に対する環境整備教育に使用する予定である.

著者

Yasuhiro Fukushima Hiromi Hirasawa Yoshito Tsushima

出版者

The Kitakanto Medical Society

雑誌

北関東医学 (ISSN:13432826)

巻号頁・発行日

vol.72, no.4, pp.349-354, 2022-11-01 (Released:2023-01-27)

参考文献数

9

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Aim: To evaluate the effectiveness of radiation protection training among medical students using X-ray equipment.Methods: Medical students attended a training class in diagnostic radiology. This training class began with a lecture on radiation protection, followed by experiments to measure the radiation dose. At the beginning and end of the training class, participants answered five-choice questions regarding the three principles of external radiation protection and the dose reduction rate of the lead apron. We also asked participants to provide free-text answers regarding what they learned from the training class and then conducted a text-mining analysis.Results: In the question regarding the three principles of external radiation protection, only 86% of students correctly answered “time” before the training class, but almost all respondents answered the question correctly after the training class. Before the training class, 81% of the students answered that the shielding rate of the lead apron was 95%, but after the training class, almost all students answered correctly that the shielding rate was 80%. Text-mining showed a co-occurrence network consisting of 10 subgraphs from the frequently occurring words.Conclusion: Having the students conduct measurement experiments on their own was effective for improving their understanding of radiation protection.

著者

安田 正人 安部 正敏 田村 敦志 石川 治

出版者

The Kitakanto Medical Society

雑誌

北関東医学 (ISSN:13432826)

巻号頁・発行日

vol.52, no.6, pp.469-472, 2002-11-01 (Released:2009-10-21)

参考文献数

10

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21歳, 男性.屋外作業時の全身の無汗と皮膚の痛みを主訴に来院.初診時, 手掌, 足底, 額部, 頸部, 上胸部, 腋窩, 外陰にわずかに発汗を認めたものの, それ以外のほぼ全身の皮膚は乾燥していた.入院後施行した発汗テストで発汗はなく, 患部皮膚の病理組織学的所見ではエックリン汗腺周囲に軽度の単核球浸潤を認めるのみであった.精査の結果, 明らかな基礎疾患を見出し得なかったことから特発性後天性無汗症と診断した.ステロイドパルス療法2クール実施後に症状は軽快した.

著者

小林 敏宏 曽根 克彦 小林 富男 小須田 貴史 田端 裕之 鈴木 隆 小野 真康 田代 雅彦

出版者

The Kitakanto Medical Society

雑誌

北関東医学 (ISSN:00231908)

巻号頁・発行日

vol.41, no.2, pp.335-340, 1991-03-01 (Released:2009-10-21)

参考文献数

8

被引用文献数

1 1

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橈骨動脈注入による逆行性大動脈造影は, 侵襲の少ない検査であり, 新生児, 乳児期に左心系造影が必要となる大動脈縮窄症, 大動脈弓離断症などの疾患には有用な検査方法である.また, 最近では肺動脈閉鎖を伴う動脈管依存性先天性心疾患の肺動脈造影にも応用されている. 当院では過去8年間に43例に対し橈骨動脈造影による診断を行なった. 疾患は, 大動脈弓の異常を呈する疾患28例 (大動脈弓離断症12例, 大動脈縮窄症9例, 左心低形成症候群4例, 血管輪3例), 肺動脈閉鎖を伴う動脈管依存性先天性心疾患13例 (Fallot四徴症7例, 三尖弁閉鎖症2例, 純型肺動脈弁閉鎖症1例, 単心室1例, 無脾および多脾症候群2例), 動脈管開存症2例であった.方法は, 22Gまたは24Gのangiocathを橈骨動脈へ経皮的に穿刺し, イオヘキソール1~2ml/kgを機械的に約2秒間で注入した.造影は全例診断可能な所見が得られ, 重篤な副作用もみられなかった.

著者

Takayuki Yamada Susumu Ohwada

出版者

The Kitakanto Medical Society

雑誌

北関東医学 (ISSN:13432826)

巻号頁・発行日

vol.72, no.1, pp.87-89, 2022-02-01 (Released:2022-03-18)

参考文献数

8

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Axillary lymphadenopathy is a local reaction to mRNA COVID-19 vaccination. A 19-year-old healthy woman presented with a mass in the axilla diagnosed by ultrasonography as a result of COVID-19 vaccine-induced hyperreactive lymphadenopathy. After two weeks, ultrasonography revealed that the lymph node had shrunk and that the blood flow signal in the hilum had disappeared. This case describes the typical course of isolated unilateral axillary lymphadenopathy after BNT162b2 COVID-19 vaccination. Short-term ultrasound is sufficient for monitoring unilateral axillary lymphadenopathy following recent COVID-19 vaccination, avoiding unnecessary radiation injury and axillary lymph node biopsies.

著者

土岐 典子 齊藤 泰之 入澤 寛之 佐倉 徹 宮脇 修一

出版者

The Kitakanto Medical Society

雑誌

北関東医学 (ISSN:13432826)

巻号頁・発行日

vol.53, no.4, pp.393-396, 2003-11-01 (Released:2009-10-21)

参考文献数

10

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症例は34歳, 女性.急性リンパ性白血病のため, 2002年5月当院入院.寛解導入療法にて寛解となったが, 1回目の地固め療法後に再発.化学療法にて2回目の寛解となったが, 予後を考慮し, 幹細胞移植を行うべくドナー検索を行った.しかし, HLAmatchドナーは家族内, 骨髄バンクでも見つからなかった.このため2002年10月, 非血縁者間臍帯血移植を施行.前処置は, TBI (total body irradiation) +CY (cyclophosphamide) で, GVHD予防にはFK506+短期MTXを使用し, 細胞数は3.02×107/kgで, HLAは3座不一致 (A locus 2座不一致, Blocusl座不一致) であった.Day22に生着し, 急性GVHDは発症せず, day100で免疫抑制剤を中止した.8ヶ月たった現在, 再発なく外来通院中である.臍帯血移植は, 小児のみでなく, 成人においても有用な治療手段である.

著者

鏑木 豊

出版者

The Kitakanto Medical Society

雑誌

北関東医学 (ISSN:00231908)

巻号頁・発行日

vol.35, no.2, pp.143-152, 1985-04-10 (Released:2009-10-15)

参考文献数

30

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In order to investigate the metabolism and mechanism of action of testosterone in the central nervous system, the following experiments were performed : 1. The pathway of testosterone metabolism in the anterior pituitary and the hypothalamus of male Wistar rats was analyzed using GC-MS. Main metabolites were identified as androst-4-ene-3, 17-dione, 5α-androstan-17β-ol-3-one, 5α-androstane-3α, 17β-diol, 5α-androstane-3β, 17β-diol, androst-4-ene-3α, 17β-diol and androst-4-ene-3β, 17β-diol.2. The metabolism of androst-4-ene-diol into 5α-androstanediol in the CNS was then analyzed using androst-4-ene-3α, 17β-diol-3-D1 (D = deuterium) and androst-4-ene-3β, 17β-diol-3-D1 as the incubation substrate. Twenty to thirty percent of androst-4-ene-3α, 17β-diol was converted directly into 5α-androstane-3α, 17β-diol, but androst-4-ene-3β, 17β-diol was not converted into 5α-androstane-3β, 17β-diol.3. Change in 5α-reductase activity in the CNS after castration was analyzed by measuring the amount of 5α-reduced metabolites (5α-DHT & 5α-androstanediol) formed by the incubation of testosterone-14C with a homogenate of the CNS tissues.It was evident that the 5α-reductase activity of the pituitary increased 5-fold at 5 weeks after castration, but in the hypothalamus no significant change was recognized.

著者

大久保 滋郎

出版者

The Kitakanto Medical Society

雑誌

北関東医学 (ISSN:00231908)

巻号頁・発行日

vol.31, no.2, pp.71-85, 1981-05-15 (Released:2009-10-15)

参考文献数

38

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上皮小体摘出時に形成される家ウサギ切歯象牙質縞模様石灰化像と成長速度の抑制, PTHレベルおよび血清Ca量の減少を指標として, パロチンとPTH製剤カケルビンの作用を比較検討した.1) 栄研PTH-キットがウサギ血中PTHの測定に使用できることを確かめたのち, 上皮小体摘出によって従来の報告のごとく象牙質の石灰化不全, 発育抑制とともに血清PTH, 血清Ca量の減少が起こることを知った.2) 正常ウサギにパロチン (Lot EJ25E510) を1mg/kg静注すると, 血清PTH量とCa量の減少と象牙質石灰化像の促進を生じ, 増量3mg/kgでは血清PTHレベル, Caの減少をきたすが, 象牙質石灰化像では一過性の促進後抑制像を引き起こすことを確認した.また, カケルビン100u/kg静注は, 血清PTHレベルとCa量の一過性増量と, 成長速度に多少の抑制を生じたが象牙質縞模様石灰化像には影響が少なかった.3) パロチンは少量1mg/kgで上皮小体摘出の欠損症状である象牙質縞模様石灰化不全, 血中PTHレベル, Caの減少をカケルビン100u/kg静注時よりもより強く回復させたが, 象牙質の成長速度の回復は明らかではなかった。この場合, 初めに縞模様石灰化像の回復が起こり, 次いで血清PTHレベルとカルシウム量が相関しつつ回復するようであった.増量3mg/kgでは血清PTH量やCaの減少を回復させたが, 象牙質縞模様石灰化像ではその回復作用は弱く, 一過陛の抑制像を含むことがあった.4) 以上の成績より, 上皮小体摘出の結果生ずる石灰化抑制の場におけるパロチンとPTHの石灰化促進作用は本質的には同じであり, パロチンはPTH様の作用を持つと考えられる.しかし血清Caの影響にみられるように, 詳細な点では, PTHと若干の差があると思われた.

著者

神宮司 洋一

出版者

The Kitakanto Medical Society

雑誌

北関東医学 (ISSN:00231908)

巻号頁・発行日

vol.28, no.3, pp.185-209, 1978-06-30 (Released:2009-11-11)

参考文献数

46

被引用文献数

1

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On the development of mammalian diaphragm it is generally accepted that the muscle of diaphragm was derived from lower cervical myotomes. In the recent, however, it was described on the diaphragm of xenopus, which was consisted of pars ventralis and pars dorsalis, that the latter one was derived developmentally from the mesoderms of forelimb bud.To compare the origin and migration of muscle of mammalian diaphragm with those of xenopus, the author has investigated the development of mouse diaphragm by means of light and electron microscopy on the embryos aged from 9.25 through 12.5 gestational days. The graphic reconstructions traced from photomicrographs taking from the tinctorially examined serial sections are available for the present study.From these observations the following results are obtained;1) The most part of diaphragmatic premuscle mass arises from the ventral edges of 4th and 5th cervical myotomes at early limb bud period (9.75-10.25 gestational days), and secondarily it migrates ventrolaterally toward the dorsal part of transverse septum during at early to late limb bud periods (9.75-11.5 g.d.).2) Only at the late limb bud period (10.5-11.5 g.d.) the diaphragmatic premuscle mass, which was just mentioned in 1), comes into contacts with the proximal border of the mesoderms of forelimb bud, and it appears that the former premuscle mass has received some part of the latter mesoderms during this period. With further development, the diaphragmatic premuscle mass after receiving some part of mesoderms from forelimb bud has migrated far ventral to the transverse septum; thus the contribution of the mesoderm of forelimb bud to the development of diaphragm has been demonstrated in mouse embryos as in xenopus.3) During the process of migrations, the diaphragmatic premuscle mass has mainly consisted of presumptive myoblasts which were characterised by its spindle shapes and numerous free ribosomes with no detectable myofibrils in their cytoplasms.Appearance of myoblasts containing myofibrils is proven in the transverse septum firstly at the later stage (12.5 g.d.) when the premuscle mass has arrived its definitive sites.

著者

橋本 省三

出版者

The Kitakanto Medical Society

雑誌

北関東医学 (ISSN:00231908)

巻号頁・発行日

vol.30, no.6, pp.357-369, 1981-02-10 (Released:2010-11-22)

参考文献数

42

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As a method to make clear the reason why congenital dislocation of the hip is found more frequently in females than males, the differeences of the shapes of the pelves between male and female infants were investigated roentgenographically.Following measurements were taken upon the correctly taken X-ray photographs of the pelves of 287 normal male and female infants who were 0 month to 3 years of age, and of 57 dislocated infants of the same ages.a : The distance between the most outside points of the bilateral ilia.b : The distance between the most inside points of the bilateral ilia at the Y cartilages.c : The distance between the most inferior points of the bilateral ilia.d : The distance between the most outside points of the bilateral ischia.e : The distance between the most inferior points of the bilateral ilia at the sacro-iliac joints.f : The distance between the most inferior point of the bilateral ischia.θ : Acetabular angle (described only in normal infants) And the ratios : b/a, c/a, d/a, e/a, f /a, f /d, were calculated in each pelvis, and examined the change of the shapes of the pelves during their growth, and also examined the differences between males and females, normal and dislocated infants.The results obtained were as follows : 1) The sexual differences were found already in the neonatal pelves.2) Observing a pelvis as a whole, the constriction which occurs around the bilateral hip joints during the growth seems to correspond with the decrease of its acetabular angle.3) The constriction around the bilateral hip joints, and the rate of the growth between the major and the minor pelvis were distinct sexual differences of the pelvis.4) In the case of congenital dislocation of the hip, it should seem that even on the male the pelvis showed the similar shape and the process of growth to the female.

著者

TSUNEHIRO ISHIDA NORITAKA SUGAMATA YOSHIKI TAKAI JUN HORIGUCHI YUKIKO KOIBUCHI TAKAO YOKOE YUICHI IINO YASUO MORISHITA TETSUNARI OYAMA TAKASHI JOSHITA

出版者

The Kitakanto Medical Society

雑誌

The KITAKANTO Medical Journal (ISSN:00231908)

巻号頁・発行日

vol.43, no.5, pp.519-524, 1993-09-01 (Released:2009-10-21)

参考文献数

16

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甲状腺癌術前診断における穿刺吸引細胞診の有用性を検討した.1975年から1992年間に穿刺吸引細胞診を施行し, 病理組織診断が判明した結節性甲状腺腫1,540例 (甲状腺癌580例, 良性腫瘍943例, 橋本病17例) を対象とした.穿刺吸引細胞診の診断能は, sensitivity 85%, specificity 93%, accuracy 90%であった.甲状腺癌では乳頭癌の正診率が90%と高く, 濾胞癌で60%と不良であった.1.0cm以下以下の微小癌にも高い正診率 (89%) が得られた.良性腫瘍の正診率は高いが, 橋本病で偽陽性が多くみられた.甲状腺癌の各種診断法の正診率を比較すると, 穿刺吸引細胞診は触診法や超音波検査に比べ良好な成績であった.以上, 穿刺吸引細胞診は甲状腺結節の良悪性診断のみならず, 組織型の推定, 微小癌の診断に有用かつ信頼度が高く, 初診時の必須検査法とすべきである.

著者

大崎 千尋

出版者

The Kitakanto Medical Society

雑誌

北関東医学 (ISSN:00231908)

巻号頁・発行日

vol.10, no.3, pp.316-328, 1960

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Investigations were made on the P<SUP>32</SUP> incorporation into the phospholipid fractions in thoracic muscle of dragon fly comparing with heart and femoral muscles of rat. The results obtained by the paperchromatographic method of Dawson were as follows : <BR>1) The total phosphatidylserine, phosphatidylethanolamine and phosphatidylcholine content was more than 70% of the total phospholipids in thoracic muscle of dragon fly, but the diphospho-in ositide content was low.<BR>2) The incoporation of P<SUP>32</SUP> into phosphatidylserine reached its maximum three hours after the ingestion of P<SUP>32</SUP>, but those into phosphatidylcholine and two unidentified substances (Rf value of them was about 0.25 in paperchromatography by phenol-NH<SUB>3</SUB>) were gradually increased ouere period of 20 hours. After 20 hours of P<SUP>32</SUP> ingestion, more than 80% of P<SUP>32</SUP> incorporated into total phospholipids were in the fractions of phosphatidylcholine and two unidentified substances referred to above.<BR>3) The composition of phospholipids of heart and femoral muscles of rat after intraperitoneal injection of P<SUP>32</SUP> were almost the same as that of dragon fly. The P<SUP>32</SUP> incorporation into diphospho-inositide and two unidentified substances of heart muscle of rat were greater than that of femoral muscle after 12 hours, while that of phosphatidylserine was the reverse.<BR>The results were discussed as to the significance of phospholipids as an important endogenous substrate of muscles, especially of insect flight muscle.

著者

大久保 滋郎

出版者

The Kitakanto Medical Society

雑誌

北関東医学 (ISSN:00231908)

巻号頁・発行日

vol.31, no.2, pp.71-85, 1981

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上皮小体摘出時に形成される家ウサギ切歯象牙質縞模様石灰化像と成長速度の抑制, PTHレベルおよび血清Ca量の減少を指標として, パロチンとPTH製剤カケルビンの作用を比較検討した.<BR>1) 栄研PTH-キットがウサギ血中PTHの測定に使用できることを確かめたのち, 上皮小体摘出によって従来の報告のごとく象牙質の石灰化不全, 発育抑制とともに血清PTH, 血清Ca量の減少が起こることを知った.<BR>2) 正常ウサギにパロチン (Lot EJ25E510) を1mg/kg静注すると, 血清PTH量とCa量の減少と象牙質石灰化像の促進を生じ, 増量3mg/kgでは血清PTHレベル, Caの減少をきたすが, 象牙質石灰化像では一過性の促進後抑制像を引き起こすことを確認した.また, カケルビン100u/kg静注は, 血清PTHレベルとCa量の一過性増量と, 成長速度に多少の抑制を生じたが象牙質縞模様石灰化像には影響が少なかった.<BR>3) パロチンは少量1mg/kgで上皮小体摘出の欠損症状である象牙質縞模様石灰化不全, 血中PTHレベル, Caの減少をカケルビン100u/kg静注時よりもより強く回復させたが, 象牙質の成長速度の回復は明らかではなかった。この場合, 初めに縞模様石灰化像の回復が起こり, 次いで血清PTHレベルとカルシウム量が相関しつつ回復するようであった.増量3mg/kgでは血清PTH量やCaの減少を回復させたが, 象牙質縞模様石灰化像ではその回復作用は弱く, 一過陛の抑制像を含むことがあった.<BR>4) 以上の成績より, 上皮小体摘出の結果生ずる石灰化抑制の場におけるパロチンとPTHの石灰化促進作用は本質的には同じであり, パロチンはPTH様の作用を持つと考えられる.しかし血清Caの影響にみられるように, 詳細な点では, PTHと若干の差があると思われた.

著者

牧野 総太郎

出版者

The Kitakanto Medical Society

雑誌

北関東医学 (ISSN:00231908)

巻号頁・発行日

vol.21, no.2, pp.104-113, 1971 (Released:2009-10-15)

参考文献数

29

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Naramycinを無条件刺激, 0.0001% Anise Oil, 0.0001%Clove Oilを条件刺激として摂水行動により'におい'の識別能力を調べた.そして前交連前枝や外嗅索を切断し, また嗅球を除去してそれが喫におい'識別能力におよぼす影響をしらべ, これらの神経系が'におい'の識別において果たす役割とその大きさを研究した.1 無処置正常ラットは約6日間の識別学習によって完全に'におい'の識別が可能となった.'におい'の組合せを変えて学習を反復すると識別条件反応の成立は次第に早くなった.2 'におい'の識別学習を終えたラットの片側の嗅球を除去すると識別能力は低下するが, 日と共に徐々に回復して22ないし25日後にほぼ完全に回復することが明らかにされた.しかし両側嗅神経系による識別能力を片側だけで完全に代償できないことも分った.また, 嗅球のレベルにおいては'におい'識別に関して左右の優位性はなかった.3 前交連前枝切断と外嗅索切断は共に'におい'の識別学習の効果を低下させたが, 後者の方が影響が大であった.また切断後の識別能力においても後者の方がより大きい影響を与えた.その点でA.C.Allisonの言うように外嗅索が'におい'のより精密な識別の役割をはたしていると思われる.4 両側の前交連前枝と外嗅索を全部切断したラット群は, 両側の嗅球を除去した群にくらべ識別学習においても, 切断手術後の識別能力の回復においても, はるかにすぐれていた. これは第3の嗅覚経路の存在を示唆するものである.5 三叉神経は'におい'の識別に関与するが'におい'識別力全体からみればその役割は小さいと考えられる.

著者

Hatsue Ogawara Kimio Morita Fumiko Hara Jun Tsuchiya

出版者

The Kitakanto Medical Society

雑誌

北関東医学 (ISSN:13432826)

巻号頁・発行日

vol.47, no.1, pp.9-14, 1997-01-01 (Released:2009-10-15)

参考文献数

23

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The clinical significance of serum beta-2 microglobulin (Sβ2M) levels in hematological malignancies and of the ratio of measured β2M value to calculated β2M (β2M M/CTD ratio) from the serum creatinine level for assessing renal function were examined. The levels of Sβ2M in patients with multiple myeloma (MM), polycythemia vera (PV), and renal failure were markedly increased. The β2M M/CTD ratio was increased in MM and PV patients, but was not increased in renal failure patients, suggesting that the β2M M/CTD ratio is useful for distinguishing between MM and renal failure.In the MM group, the mean Sβ2M level did not significantly differ between the patients who received chemotherapy with/without interferon and those who were not treated. However, the mean β2M M/CTD ratio of the chemotherapy plus interferon-alpha group was significantly higher than that of the non-treated group (p <0.01) and that of the chemotherapy-only group (p < 0.02). In the group with chronic myelogenous leukemia, both the mean Sβ2M level and the mean β2M M/CTD ratio were significantly different in the non-treated patients compared with the interferon therapy patients (p <0.02, p <0.05).We speculate that the evaluation of prognosis and tumor mass by the level of Sβ2M should be performed at the time of diagnosis, before the administration of chemotherapy with interferon.

著者

内山 喜久雄

出版者

The Kitakanto Medical Society

雑誌

北関東医学 (ISSN:00231908)

巻号頁・発行日

vol.9, no.4, pp.772-785, 1959-07-01 (Released:2009-10-21)

参考文献数

45

被引用文献数

1 1

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The statistical survey has been made on the forty-six cases of the childhood mutism from among the 24, 245 pupils of the whole elementary schools in the City M., by means of the diagnostic interview and the questionnaire method. The childhood mutisms were observed Tin 0.19% of the whole pupils, girls exceeding boys in the frequency.The personal and environmental factors which may bring about anxiety and feeling of isolation on the part of the patients producing negativistic responses such as mutism are as follows : The personal factors contributing to infantile mutism were intellectual retardation and consequently poor academic achievement with delayed commencement of speech and walking. Notable diseases in the past, and nervous habits in the past and present are often considered as contributing factors. Although the problem of the heredity of the mutistic trends needs further considerations, patients' near relatives surveyed showed comparatively frequent occurrences of mutism. The psychiatric survey of the patients' present physical conditions revealed no direct relationships with mutism, with the exceptions of some physical indications for some of the mentally deficient subjects.As for environmental factors, the attitudes of their parents' laissez-faire and their mothers' over-protection may be influential in producing mutism. It was noticed that the academic career and socio-economic status of the parents were considerably low. Among the effects of the grandparents' attitudes contributing to the formation of the symptom, the grandmothers' over-protection should be emphasized. In some cases, sibling rivalry might also be regarded as a factor, but in this respect, further observation may be demanded. The numbers of the patients' friends and playmates are remarkably few, which might in turn promote the mutistic trends. Situations causing the childhood mutism are found chiefly in and around schools and unacquainted places, being scarcely seen in the home and neighbourhood situations.

著者

河野 恵 山本 孝 松田 忠泰 佐藤 重房 長崎 宗俊

出版者

The Kitakanto Medical Society

雑誌

北関東医学 (ISSN:00231908)

巻号頁・発行日

vol.10, no.3, pp.458-460, 1960-05-01 (Released:2009-10-21)

参考文献数

9

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Three ointments, Merzonin-ointment, Mercurochromum-ointment and Unguentum Hydrargyri, were used in a Preliminary Screening Test in an attempt to determine which ointments would warrant further testing for protective agents against the penetration of larvae of Ancylostoma caninum.No remarkable effective result were found compared with the control.

著者

小此木 丘 星 昭二 本間 学 須藤 謙三郎 飯塚 久義 佐藤 信

出版者

The Kitakanto Medical Society

雑誌

北関東医学 (ISSN:00231908)

巻号頁・発行日

vol.12, no.3, pp.199-207, 1962 (Released:2009-11-11)

参考文献数

15

被引用文献数

2 1

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An injection of Habu-snake venom, heated for 10 minutes at 100°C., caused myolysis at the site, histologically. But different from crude venom action, no hemorrhagic changes were recognized. At first, disappearance of mitchondria in the muscular fibers was seen, and then muscular splitting and lysis followed.While the myolytic changes caused by crude venom began immediately af ter the injection, the beginning of the changes were delayed when the heated material were used.Anti-Habu-serum neutralised the toxicity of the heated venom, and also, E.D.T.A.-Ca, Cocarboxylase and α-Thiolactoylglicine-Na repressed the toxicity in vitro.