著者

安藤 桃子 杉村 和紀 上高原 浩

出版者

公益社団法人 日本材料学会

雑誌

材料 (ISSN:05145163)

巻号頁・発行日

vol.70, no.7, pp.547-553, 2021-07-15 (Released:2021-07-20)

参考文献数

30

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Liquid crystallinity of (hydroxypropyl)cellulose (HPC) derivative in aqueous solution was examined to develop eco-friendly liquid-crystalline system. Bulky adamantoyl group (adamantyl ester) was introduced as a substituent on HPC, and the effects of the degree of adamantoyl substitution (DSAd), polymer concentration, and temperature on the chiroptical properties, especially coloration and turbidity, of the aqueous lyotropics were investigated by circular dichroism, CD, and ultraviolet–visible–near-infrared, UV–Vis–NIR, spectrophotometry. Adamantates of HPC (Ad- HPCs) with extremely low DSAd (< 0.1) were successfully synthesized by acylation of HPC with 1-adamantanecarbonyl chloride in tetrahydrofuran. Ad-HPCs of DSAd ≤ 0.08 were highly soluble in water, and the concentrated aqueous solutions formed a right-handed cholesteric liquid-crystalline phase to impart vivid reflective colorations. The cholesteric helical pitch P, comparable to the wavelength of maximal reflectance λmax, increased with increasing DSAd of Ad-HPC and with decreasing polymer concentration. Wide-angle X-ray diffractometry, WAXD, revealed that the increases of P were attributable to the decrease of the twist angle ϕ between adjacent thin nematic layers. The aqueous Ad-HPC lyotropics were phase-separated and became turbid at an elevated temperature of > ∼30°C. Such a lower critical solution temperature (LCST)-type phase separation behavior of the Ad-HPC/water system was also affected by the hydrophobic adamantoyl group; the observed cloud point Tc was shifted to lower temperature side with increase in DSAd, presumably due to the heightening of hydrophobic interactions between the solute Ad-HPCs in water.

著者

高原 浩 高原 聡

出版者

一般社団法人 日本消化器内視鏡学会

雑誌

日本消化器内視鏡学会雑誌 (ISSN:03871207)

巻号頁・発行日

vol.55, no.1, pp.22-27, 2013 (Released:2013-01-31)

参考文献数

22

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症例は31歳の女性.昼食でサバの刺身を食べ,その翌朝4時頃より腹痛,悪心を認め来院した.超音波検査で,骨盤腔に腹水があり,小腸壁の肥厚が認められた.上部消化管内視鏡で異常はなく,経口的消化管造影で,回腸の異常拡張と,それに続く肛門側回腸の狭窄,拇指圧痕所見をみとめた.経肛門的ダブルバルーン内視鏡で,大腸には異常がなかったが,回腸粘膜は終末部より著しい浮腫状を呈し,深部回腸にアニサキス虫体を発見し,生検鉗子により摘出した.腹痛は急速に消失し,腹水も二日後にはほとんど消失した.本症例は小腸アニサキスを小腸内視鏡で発見し摘出し得た初めての報告例であると考えられた.