1 0 0 0 OA 動脈血二酸化炭素分圧低下時の微小循環動態
- 著者
- 中田 智子 高田 勝美 小森 万希子 鈴木 英弘 菅原 基晃
- 出版者
- 特定非営利活動法人 日本バイオレオロジー学会
- 雑誌
- 日本バイオレオロジー学会誌 (ISSN:09134778)
- 巻号頁・発行日
- vol.11, no.3, pp.27-33, 1997-09-30 (Released:2012-09-24)
- 参考文献数
- 35
Using the rabbit ear chamber (REC) method, the author compared the effect of hypocapnia and that of normocapnia on cutaneous microcirculation of rabbits. Eight rabbits, weighting 3-4kg, were used for this study, which were anesthetized with pentobarbital and pancuronium. To maintain PaO2 at 100-150mmHg and PaCO2 at 20-25mmHg (HYPOCAPNIC GROUP), they were mechanically ventilated with air-O2 and regulated. After observing the circulation of arteriole during hypocapnia for 15-20 minutes, to induce normocapnia, 100% CO2 was added to the inspired gas stepwise until PaCO2 reached 35-45mmHg (NORMOCAPNIC GROUP). And the circulationof arteriole was observed during normocapnia for 15-20 minutes.No significant changes were observed in the blood pressure, heart rate and pulse pressure. However, significant change was observed in pH. During hypocapnia, the diameter, blood-flow velocity and blood-flow rate of the arterioles were markedly reduced (p<0.05).This study using REC has shown that hypocapnia causes cutaneous microcirculatory changes and increase systemic vascular resistance.
1 0 0 0 IR (第5回山川寿子研究奨励金受賞者研究発表)吸入酸素濃度と微小循環動態
- 著者
- 小森 万希子 高田 勝美 中田 智子 塩谷 雅子 田口 晶子 鈴木 英弘 菅原 基晃
- 出版者
- 東京女子医科大学学会
- 雑誌
- 東京女子医科大学雑誌 (ISSN:00409022)
- 巻号頁・発行日
- vol.64, no.2, pp.180-180, 1994-02-25
東京女子医科大学学会第297回例会 平成6年2月17日 東京女子医科大学 弥生記念講堂