著者

髙橋 健一郎 本間 哲 鈴木 恵子 加藤 文代 杉原 茂孝

出版者

東京女子医科大学学会

雑誌

東京女子医科大学雑誌 (ISSN:00409022)

巻号頁・発行日

vol.87, no.Extra1, pp.E118-E124, 2017-05-31 (Released:2017-07-31)

参考文献数

30

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We present a case of Kawasaki disease (KD) complicated by clinically mild encephalitis/encephalopathy with a reversible splenial lesion (MERS). A 2-year-old boy was brought to the emergency outpatient unit because of recurrent convulsions. He had experienced two episodes of KD at the age of 1 year. Both episodes had been treated with high dose intravenous immunoglobulin therapy (IVIG; 2 g/kg/day) and the patient had recovered from both episodes without any sequelae. He was diagnosed as having KD based on the presence of 5 out of 6 criteria. After hospitalization, the patient exhibited a persistent disturbance of consciousness and was diagnosed as having MERS based on the presence of enhanced signals in the splenium of the corpus callosum on the 3rd day of illness. Initial treatment with IVIG plus pulsed methylprednisolone (30 mg/kg/day×3 days) for MERS was started. However, a high fever recurred on the 7th day. Additional treatment with IVIG plus intravenous prednisolone (2 mg/kg/day) was started on the 8th day. The patient's body temperature normalized on the 9th day and maintenance therapy with prednisolone was continued until the 28th day. Despite some risk factors for coronary artery lesion, the patient was discharged without any sequelae because of twice IVIG and aggressive steroid therapy including steroid pulse therapy.

著者

竹植 正和 髙橋 健一 稲葉 通将

雑誌

研究報告コンピュータと教育(CE)

巻号頁・発行日

vol.2014-CE-124, no.17, pp.1-8, 2014-03-07

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e -ラーニングでは,学習場所の制約を比較的受けずに自分のペースで学習を行うことができる.一方,学習を進めるうちに次第に飽きてくる傾向がある.本研究では,学習の合間に気分をリフレッシュさせる方法のひとつとして,休憩時間に楽しさを取りいれたゲームを行うことを取り上げ,実験によりその効用を調べる.実験においては.休憩時間に比較的忙しいゲーム,ゆったりとしたゲームをするグループと何もしないグループに学習者を分けて,数式を解く問題を被験者に行わせる.これらのグループの実験結果とアンケートによりこれらのゲームの影響について考察する.