著者

鈴木 輝明 武田 聡 鈴木 稔 黒沢 悦朗

出版者

天然有機化合物討論会

雑誌

天然有機化合物討論会講演要旨集

巻号頁・発行日

no.29, pp.576-583, 1987-07-25

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In our continuing work on the neutral extract of Laurencia obtusa (magiresozo in Japanese), which exhibited the remarkably cytotoxic properties, we previously reported the isolation and structure determination of strongly active squalene-derived polyethers. Further investigation of this extract has led to the isolation of five cytotoxic diterpenes (1)-(5), which are structurally related to parguerol or isoparguerol, along with inactive sesquiterpenes (6)-(9). The structures of these compounds were characterized by chemical and spectral methods.