- 著者
- Wei-Syun Hu Cheng-Li Lin
- 出版者
- 日本循環器学会
- 雑誌
- Circulation Journal (ISSN:13469843)
- 巻号頁・発行日
- pp.CJ-17-0130, (Released:2017-06-16)
- 参考文献数
- 32
- 被引用文献数
- 6
Background:The aim of this study was to assess the accuracy of CHA2DS2-VASc score in predicting new-onset atrial fibrillation (AF) in patients with chronic obstructive pulmonary disease (COPD).Methods and Results:A total of 50,430 COPD patients were enrolled in this study. The area under the receiver operating characteristic curve (AUC) and the Cox model c-statistic were used to assess the association between new-onset AF risk and CHA2DS2-VASc score in COPD patients. After adjustment for comorbidities other than the components of CHA2DS2-VASc score, risk of new-onset AF in COPD patients increased from 1.24 (95% confidence interval (CI): 1.01–1.52) for a score of 1, to 2.15 (95% CI: 1.62–2.86) for score ≥6 (trend test, P<0.001), compared with CHA2DS2-VASc score 0. The AUC for CHA2DS2-VASc score in predicting new-onset AF in COPD patients was 0.69 (95% CI: 0.68–0.70). The c-statistic of Cox model in predicting incident AF was 0.73.Conclusions:Risk of new-onset AF in COPD patients increased with increasing CHA2DS2-VASc score. The predictive ability of the score was moderate. CHA2DS2-VASc score might be used as a screening tool for AF in COPD patients.
- 著者
- Wei-Syun Hu Cheng-Li Lin
- 出版者
- Japan Atherosclerosis Society
- 雑誌
- Journal of Atherosclerosis and Thrombosis (ISSN:13403478)
- 巻号頁・発行日
- pp.48835, (Released:2019-06-22)
- 参考文献数
- 20
- 被引用文献数
- 7
Aim: The objective was to compare the rate of atrial fibrillation (AF) onset in patients with congenital heart disease (CHD) compared to controls.Methods: Using a large number of samples extracted from nationwide cohort data in Taiwan, the authors used a propensity-matching procedure and multivariable Cox models to assess the risk of AF by CHD.Results: A cohort of 19,439 CHD patients and a propensity-matched cohort of 19,439 control patients were included in this study. The cumulative incidence of AF was significantly higher in the CHD cohort than in the non-CHD cohort (p<0.001). After controlling for confounding factors, the adjusted hazard ratio (aHR) of AF was 4.23 (95% confidence interval [CI] 3.31–5.41) in the CHD cohort, compared to the non-CHD cohort.Conclusions: A significant association between CHD and AF risk was found.
- 著者
- Shih-Yi Lin Cheng-Li Lin Wu-Huei Hsu I-Kuan Wang Chiz-Chung Chang Chiu-Ching Huang Chia-Hung Kao Shu-Hui Liu Fung-Chang Sung
- 出版者
- (公社)日本産業衛生学会
- 雑誌
- Journal of Occupational Health (ISSN:13419145)
- 巻号頁・発行日
- vol.55, no.3, pp.158-166, 2013 (Released:2013-10-04)
- 参考文献数
- 36
- 被引用文献数
- 1 8
Background: Physicians are frequently studied as a population that experiences extremely high stress, burnout, and prolonged working hours that might harm one's health. However, they have sound medical knowledge and have easy access to medical resources. We studied the incidence of cancer among Taiwanese physicians using a nationwide cohort study design. Methods: Data were obtained from the National Health Insurance (NHI) system in Taiwan. The physician cohort contained 22,309 physicians, and each physician was randomly frequency-matched according to age and sex with 4 people from the general population. Results: The overall incidence ratio of cancer was 27% lower in the physician cohort than in the nonphysician comparison cohort (33.9 vs. 46.5 people per 10,000 person-years, crude hazard ratio (HR)=0.73, 95% CI=0.70, 0.76). The adjusted HR was 0.78 (95% CI=0.72, 0.84). Female physicians experienced a higher incidence rate ratio of overall cancer, compared to male physicians (crude HR=1.17, 95% CI=1.03, 1.33 vs. crude HR=0.70, 95% CI=0.67, 0.74, respectively). Physicians were at a significantly higher risk of thyroid cancer (HR 1.75, 95% CI=1.14, 2.68), prostate cancer (HR=1.54, 95% CI=1.21, 1.97), breast cancer (HR=1.45, 95% CI=1.00, 2.09), and non-cervical gynecological cancer (HR=4.03, 95% CI=1.77, 9.17), compared with the general population. Conclusions: Physicians are at lower overall risk of cancer than the general population, apart from cancer of the thyroid, prostate, breast, and non-cervical gynecological cancer.(J Occup Health 2013; 55: 158–166)
- 著者
- Shih-Yi Lin Cheng-Li Lin Wu-Huei Hsu I-Kuan Wang Chiz-Chung Chang Chiu-Chin Huang Chia-Hung Kao Shu-Hui Liu
- 出版者
- (公社)日本産業衛生学会
- 雑誌
- Journal of Occupational Health (ISSN:13419145)
- 巻号頁・発行日
- pp.12-0263-OA, (Released:2013-04-09)
- 被引用文献数
- 1 8
Background: Physicians are frequently studied as a population that experiences extremely high stress, burnout, and prolonged working hours that might harm one’s health. However, they have sound medical knowledge and have easy access to medical resources. We studied the incidence of cancer among Taiwanese physicians using a nationwide cohort study design. Methods: Data were obtained from the National Health Insurance (NHI) system in Taiwan. The physician cohort contained 22,309 physicians, and each physician was randomly frequency-matched according to age and sex with 4 people from the general population. Results: The overall incidence ratio of cancer was 27% lower in the physician cohort than in the nonphysician comparison cohort (33.9 vs. 46.5 people per 10,000 person-years, crude hazard ratio (HR) = 0.73, 95% CI = 0.70, 0.76). The adjusted HR was 0.78 (95% CI = 0.72, 0.84). Female physicians experienced a higher incidence rate ratio of overall cancer, compared to male physicians (crude HR = 1.17, 95% CI = 1.03, 1.33 vs crude HR = 0.70, 95% CI = 0.67, 0.74, respectively). Physicians were at a significantly higher risk of thyroid cancer (HR 1.75, 95% CI = 1.14, 2.68), prostate cancer (HR = 1.54, 95% CI = 1.21, 1.97), breast cancer (HR = 1.45, 95% CI = 1.00, 2.09), and non-cervical gynecological cancer (HR = 4.03, 95% CI = 1.77, 9.17), compared with the general population. Conclusion: Physicians are at lower overall risk of cancer than the general population, apart from cancer of the thyroid, prostate, breast, and non-cervical gynecological cancer.