著者

Jing ZHANG Dan LI Hong-an LI Xuewen LI Lizhi ZHANG

出版者

The Institute of Electronics, Information and Communication Engineers

雑誌

IEICE TRANSACTIONS on Information and Systems (ISSN:09168532)

巻号頁・発行日

vol.E106-D, no.2, pp.229-239, 2023-02-01

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In order to solve the low-quality problems such as low brightness, poor contrast, noise interference and color imbalance in night images, a night image enhancement algorithm based on MDIFE-Net curve estimation is presented. This algorithm mainly consists of three parts: Firstly, we design an illumination estimation curve (IEC), which adjusts the pixel level of the low illumination image domain through a non-linear fitting function, maps to the enhanced image domain, and effectively eliminates the effect of illumination loss; Secondly, the DCE-Net is improved, replacing the original Relu activation function with a smoother Mish activation function, so that the parameters can be better updated; Finally, illumination estimation loss function, which combines image attributes with fidelity, is designed to drive the no-reference image enhancement, which preserves more image details while enhancing the night image. The experimental results show that our method can not only effectively improve the image contrast, but also make the details of the target more prominent, improve the visual quality of the image, and make the image achieve a better visual effect. Compared with four existing low illumination image enhancement algorithms, the NIQE and STD evaluation index values are better than other representative algorithms, verify the feasibility and validity of the algorithm, and verify the rationality and necessity of each component design through ablation experiments.

著者

Ji Yin Zhou Shi Wen Zhou Ke Bin Zhang Jian Lin Tang Li Xia Guang Yi Ying Ying Xu Le Zhang Dan Dan Li

出版者

公益社団法人日本薬学会

雑誌

Biological and Pharmaceutical Bulletin (ISSN:09186158)

巻号頁・発行日

vol.31, no.6, pp.1169-1176, 2008-06-01 (Released:2008-06-01)

参考文献数

37

被引用文献数

61 114

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Berberine is one of the main alkaloids of Rhizoma coptidis which has been used as a folk medicine to treat diabetes mellitus for more than 1400 years in China. To investigate the chronic effect of berberine on diabetic hyperlipidemic rats, fasted rats were intraperitoneally injected 35 mg/kg streptozotocin. Diabetic rats were admitted after 2 weeks and given a high-carbohydrate/high-fat diet to induce hyperlipidemia. The rats were divided into 7 groups at the end of week 16: normal and diabetic rats received no drug, 5 treatment groups were administered with either 75, 150, 300 mg/kg berberine, 100 mg/kg fenofibrate or 4 mg/kg rosiglitazone per day for 16 weeks, respectively. The blood glucose, hemoglobin A1c, lipid metabolic parameters and hepatic glycogen and triglyceride were measured, and histopathology and peroxisome proliferator-activated receptors (PPARs) α/δ/γ expression of liver were determined by hematoxylin eosin and immunohistochemical staining. Berberine reduced diabetic rats' body weight, liver weight and liver to body weight ratio. Berberine restored the increased blood glucose, hemoglobin A1c, total cholesterol, triglyceride, low density lipoprotein-cholesterol, apolipoprotein B and the decreased high density lipoprotein-cholesterol, apolipoprotein AI levels in diabetic rats to near the control ones. Berberine alleviated the pathological progression of liver and reverted the increased hepatic glycogen and triglyceride to near the control levels. Berberine increased PPARα/δ expression and reduced PPARγ expression in liver of diabetic rat to near the control ones. Berberine improved glucolipid metabolism both in blood and liver in diabetic rats possibly through modulating the metabolic related PPARα/δ/γ protein expression in liver.