文献一覧: EIJI KOBAYASHI (著者)

7 0 0 0 OA Motivating Mothers to Recommend Their 20-Year-Old Daughters Receive Cervical Cancer Screening: A Randomized Study

著者: Tomomi Egawa-Takata Yutaka Ueda Akiko Morimoto Yusuke Tanaka Asami Yagi Yoshito Terai Masahide Ohmichi Tomoyuki Ichimura Toshiyuki Sumi Hiromi Murata Hidetaka Okada Hidekatsu Nakai Masaki Mandai Shinya Matsuzaki Eiji Kobayashi Kiyoshi Yoshino Tadashi Kimura Junko Saito Yumiko Hori Eiichi Morii Tomio Nakayama Mikiko Asai-Sato Etsuko Miyagi Masayuki Sekine Takayuki Enomoto Yorihiko Horikoshi Tetsu Takagi Kentaro Shimura
出版者: Japan Epidemiological Association
雑誌: Journal of Epidemiology (ISSN:09175040)
巻号頁・発行日: pp.JE20160155, (Released:2017-11-11)
参考文献数: 14
被引用文献数: 8

Background: In Japan, the rate of cervical cancer screening is remarkably low, especially among women in their twenties and thirties, when cervical cancer is now increasing dramatically. The aim of this study was to test whether a modified government reminder for 20-year-old women to engage in cervical cancer screening, acting through maternal education and by asking for a maternal recommendation to the daughter to receive the screening, could increase their participation rate.Methods: In two Japanese cities, 20-year-old girls who had not received their first cervical cancer screening before October of fiscal year 2014 were randomized into two study arms. One group of 1,274 received only a personalized daughter-directed reminder leaflet for cervical cancer screening. In the second group of 1,274, the daughters and their mothers received a combination package containing the same reminder leaflet as did the first group, plus an additional informational leaflet for the mother, which requested that the mother recommend that her daughter undergo cervical cancer screening. The subsequent post-reminder screening rates of these two study arms were compared.Results: The cervical cancer screening rate of 20-year-old women whose mothers received the information leaflet was significantly higher than that for women who received only a leaflet for themselves (11% vs 9%, P = 0.0049).Conclusions: An intervention with mothers, by sending them a cervical cancer information leaflet with a request that they recommend that their daughter receive cervical cancer screening, significantly improved their daughters’ screening rate.

2018-02-01 19:46:25
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6 0 0 0 OA Levothyroxine-Induced Liver Dysfunction in a Primary Hypothyroid Patient

著者: MASAMI OHMORI KAZUHIRO HARADA SHUICHI TSURUOKA KOH-ICHI SUGIMOTO EIJI KOBAYASHI AKIO FUJIMURA
出版者: The Japan Endocrine Society
雑誌: Endocrine Journal (ISSN:09188959)
巻号頁・発行日: vol.46, no.4, pp.579-583, 1999 (Released:2006-11-25)
参考文献数: 5
被引用文献数: 3 9

Here we report a case of levothyroxine-induced liver dysfunction. T4 (levothyroxine) has been more commonly used for the treatment of hypothyroidism than T3 active hormone (triiodothyronine), because with the former drug a stabler plasma concentration is obtained after oral administration. Although there are few reports on levothyroxine-induced liver dysfunction, we treated a primary hypothyroid patient with high serum aminotransferase after administration of levothyroxine. Liver dysfunction was improved after cessation of the drug administration. Antibody to T4 was found in the serum of the patient after this event. From clinical course and laboratory data of the patient, the episode of liver damage was considered to be induced by levothyroxine. We then administrated triiodothyronine, and it did not induce liver dysfunction. Changing levothyroxine to triiodothyronine resulted in a successful clinical course in this case, as re-administration of the doubtful drug is strictly limited.

2018-06-04 05:36:13
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1 0 0 0 OA The Effects of Hydrogen Gas Inhalation on Adverse Left Ventricular Remodeling After Percutaneous Coronary Intervention for ST-Elevated Myocardial Infarction ― First Pilot Study in Humans ―

著者: Yoshinori Katsumata Fumiya Sano Takayuki Abe Tomoyoshi Tamura Taishi Fujisawa Yasuyuki Shiraishi Shun Kohsaka Ikuko Ueda Koichiro Homma Masaru Suzuki Shigeo Okuda Yuichiro Maekawa Eiji Kobayashi Shingo Hori Junichi Sasaki Keiichi Fukuda Motoaki Sano
出版者: The Japanese Circulation Society
雑誌: Circulation Journal (ISSN:13469843)
巻号頁・発行日: vol.81, no.7, pp.940-947, 2017-06-23 (Released:2017-06-23)
参考文献数: 28
被引用文献数: 18 47

Background:Hydrogen gas inhalation (HI) reduced infarct size and mitigated adverse left ventricular (LV) remodeling in a rat model of acute myocardial infarction (AMI). We designed a prospective, open-label, rater-blinded clinical pilot study in patients experiencing ST-elevated MI (STEMI).Methods and Results:The 20 patients with an initial diagnosis of STEMI were assigned to either an HI group (1.3% H2with 26% oxygen) or a control group (26% oxygen). There were no HI-related severe adverse events. In the full analysis set, the cardiac salvage index as evaluated using cardiac magnetic resonance imaging at 7 days after primary percutaneous coronary intervention (PCI), showed no significant between-group difference (HI: 50.0±24.3%; control: 60.1±20.1%; P=0.43). However, the improvement from day 7 in the HI group was numerically greater than that in the control group in some of the surrogate outcomes at 6-month follow-up, including the LV stroke volume index (HI: 9.2±7.1 mL/m2; control: −1.4±7.2 mL/m2; P=0.03) and the LV ejection fraction (HI: 11.0%±9.3%; control: 1.7%±8.3%; P=0.11).Conclusions:The first clinical study has shown that HI during PCI is feasible and safe and may also promote LV reverse remodeling at 6 months after STEMI. The study was not powered to test efficacy and a further large-scale trial is warranted. (Clinical trials registration: UMIN00006825)

2021-02-22 22:19:46
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1 0 0 0 OA Motivating Mothers to Recommend Their 20-Year-Old Daughters Receive Cervical Cancer Screening: A Randomized Study

著者: Tomomi Egawa-Takata Yutaka Ueda Akiko Morimoto Yusuke Tanaka Asami Yagi Yoshito Terai Masahide Ohmichi Tomoyuki Ichimura Toshiyuki Sumi Hiromi Murata Hidetaka Okada Hidekatsu Nakai Masaki Mandai Shinya Matsuzaki Eiji Kobayashi Kiyoshi Yoshino Tadashi Kimura Junko Saito Yumiko Hori Eiichi Morii Tomio Nakayama Mikiko Asai-Sato Etsuko Miyagi Masayuki Sekine Takayuki Enomoto Yorihiko Horikoshi Tetsu Takagi Kentaro Shimura
出版者: Japan Epidemiological Association
雑誌: Journal of Epidemiology (ISSN:09175040)
巻号頁・発行日: vol.28, no.3, pp.156-160, 2018-03-05 (Released:2018-03-05)
参考文献数: 14
被引用文献数: 2 8

2019-01-30 10:53:20
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