- 著者
- Atsuko Uehara Yohei Kita Hirofumi Sumi Yugo Shibagaki
- 出版者
- The Japanese Society of Internal Medicine
- 雑誌
- Internal Medicine (ISSN:09182918)
- 巻号頁・発行日
- vol.58, no.15, pp.2201-2205, 2019-08-01 (Released:2019-08-01)
- 参考文献数
- 21
- 被引用文献数
- 8 13
Hypomagnesemia, a side effect of proton-pump inhibitors (PPIs), can be asymptomatic. The presence of hypocalcemia or hypokalemia is indicative of hypomagnesemia; however, the concomitant use of PPIs and thiazide may mask hypocalcemia. A 79-year-old woman with a history of chronic heart failure and chronic kidney disease developed symptomatic hypocalcemia and hypomagnesemia. Five weeks earlier, she had developed thiazide-induced hyponatremia, so thiazide had been discontinued. Reviewing the patient's charts revealed that three discontinued thiazide administrations in the clinical course had unmasked hypocalcemia. Our case demonstrates that thiazide-induced hypercalcemia can be so prominent as to mask PPI-induced hypocalcemia and hypomagnesemia.
- 著者
- Hiroyuki SHIMADA Toshiaki YAMAGUCHI Hirofumi SUMI Yuki YAMAGUCHI Katsuhiro NOMURA
- 出版者
- The Ceramic Society of Japan
- 雑誌
- Journal of the Ceramic Society of Japan (ISSN:18820743)
- 巻号頁・発行日
- vol.125, no.4, pp.257-261, 2017-04-01 (Released:2017-04-03)
- 参考文献数
- 28
- 被引用文献数
- 9 10
Perovskite-type mixed protonic and oxide ionic conductors for electrolyte material of solid oxide fuel cells were investigated, focusing on BaZr0.1Ce0.7Y0.1Yb0.1O3−δ (BZCYYb) due to its high ionic conductivity and chemical stability. BZCYYb and NiO-added BZCYYb were evaluated using electrolyte-supported cell (ESC) and anode-supported cell (ASC) samples. 2 wt.% NiO was solid solute into the BZCYYb, resulting in improvement in the sinterability and thermal-expansion behavior. The addition of NiO, however, lead to the deterioration of cell performance. Compared with the ESC, power density of the ASC was much higher due to thin electrolyte, whereas its open-circuit voltage (OCV) was lower. This is due to Ni diffusion from the NiO–BZCYYb anode into the BZCYYb electrolyte during high-temperature co-sintering process at 1350°C. From the results of OCV measurements, 0–2 wt.% NiO was considered to be dissolved in the BZCYYb electrolyte of the ASC, suggesting that controlling Ni diffusion during co-sintering process is essential to achieve higher-performance ASCs using BZCYYb.