- 著者
-
Takeshi Miyamoto
Eri Katsuyama
Hiroya Kanagawa
Atsuhiro Fujie
Hiroya Miyamoto
Shigeyuki Yoshida
Tomoaki Mori
Kana Miyamoto
Yuiko Sato
Tami Kobayashi
Masaya Nakamura
Morio Matsumoto
Yuji Nishiwaki
Hiroshi Hirose
Takeshi Kanda
Ikuo Saito
Yoshiaki Toyama
- 出版者
- The Keio Journal of Medicine
- 雑誌
- The Keio Journal of Medicine (ISSN:00229717)
- 巻号頁・発行日
- vol.65, no.2, pp.33-38, 2016 (Released:2016-06-25)
- 参考文献数
- 24
- 被引用文献数
-
11
13
Low serum 25-hydroxyvitamin D (25(OH)D) levels are implicated as a risk factor for hip and spine fractures. Studies of the relation between 25(OH)D levels and fractures have primarily involved elderly osteoporosis patients or patients with fractures; however, the serum 25(OH)D and parathyroid hormone (PTH) status in younger adult populations remains largely unknown. We evaluated serum 25(OH)D and intact PTH levels in 411 women aged 39–64 years who were not receiving medication for osteoporosis or other bone diseases. Serum 25(OH)D levels were positively correlated with age (P = 0.019), whereas intact PTH levels were inversely correlated with 25(OH)D levels (P < 0.001). Thus, low vitamin D levels with high intact PTH levels were more common in younger than in older women. Our data show that serum 25(OH)D insufficiency could be a more serious concern in the younger population than had been previously anticipated. Because serum 25(OH)D insufficiency is reportedly a risk factor for hip and spine fracture, the number of fracture patients could increase in the future, suggesting that we may need to correct the serum vitamin D/intact PTH status to prevent future osteoporosis.