著者
Takeshi Miyamoto Eri Katsuyama Hiroya Kanagawa Atsuhiro Fujie Hiroya Miyamoto Shigeyuki Yoshida Tomoaki Mori Kana Miyamoto Yuiko Sato Tami Kobayashi Masaya Nakamura Morio Matsumoto Yuji Nishiwaki Hiroshi Hirose Takeshi Kanda Ikuo Saito Yoshiaki Toyama
出版者
The Keio Journal of Medicine
雑誌
The Keio Journal of Medicine (ISSN:00229717)
巻号頁・発行日
vol.65, no.2, pp.33-38, 2016 (Released:2016-06-25)
参考文献数
24
被引用文献数
5 6

Low serum 25-hydroxyvitamin D (25(OH)D) levels are implicated as a risk factor for hip and spine fractures. Studies of the relation between 25(OH)D levels and fractures have primarily involved elderly osteoporosis patients or patients with fractures; however, the serum 25(OH)D and parathyroid hormone (PTH) status in younger adult populations remains largely unknown. We evaluated serum 25(OH)D and intact PTH levels in 411 women aged 39–64 years who were not receiving medication for osteoporosis or other bone diseases. Serum 25(OH)D levels were positively correlated with age (P = 0.019), whereas intact PTH levels were inversely correlated with 25(OH)D levels (P < 0.001). Thus, low vitamin D levels with high intact PTH levels were more common in younger than in older women. Our data show that serum 25(OH)D insufficiency could be a more serious concern in the younger population than had been previously anticipated. Because serum 25(OH)D insufficiency is reportedly a risk factor for hip and spine fracture, the number of fracture patients could increase in the future, suggesting that we may need to correct the serum vitamin D/intact PTH status to prevent future osteoporosis.

言及状況

外部データベース (DOI)

はてなブックマーク (1 users, 1 posts)

[ビタミン][ビタミンD][代謝][生化学][論文][健康][研究]

Twitter (21 users, 22 posts, 82 favorites)

https://t.co/Vo9JnX8mkr
【私見】 日本人75%以上が25OHvitaminDで100ng/mLに達してない https://t.co/LAFlr4bYhs 40000IU/日を1か月程続けてから測定 僕は4回/日に分けて飲んでるけど脂溶性だから満腹防止が理由 厚労省の推奨摂取量220IUではくる病の防止にしかならない vitaminD3で健康革命 https://t.co/JzfwksUjOb

収集済み URL リスト