- 著者
- Takeshi Miyamoto Eri Katsuyama Hiroya Kanagawa Atsuhiro Fujie Hiroya Miyamoto Shigeyuki Yoshida Tomoaki Mori Kana Miyamoto Yuiko Sato Tami Kobayashi Masaya Nakamura Morio Matsumoto Yuji Nishiwaki Hiroshi Hirose Takeshi Kanda Ikuo Saito Yoshiaki Toyama
- 出版者
- The Keio Journal of Medicine
- 雑誌
- The Keio Journal of Medicine (ISSN:00229717)
- 巻号頁・発行日
- vol.65, no.2, pp.33-38, 2016 (Released:2016-06-25)
- 参考文献数
- 24
- 被引用文献数
- 11 13
Low serum 25-hydroxyvitamin D (25(OH)D) levels are implicated as a risk factor for hip and spine fractures. Studies of the relation between 25(OH)D levels and fractures have primarily involved elderly osteoporosis patients or patients with fractures; however, the serum 25(OH)D and parathyroid hormone (PTH) status in younger adult populations remains largely unknown. We evaluated serum 25(OH)D and intact PTH levels in 411 women aged 39–64 years who were not receiving medication for osteoporosis or other bone diseases. Serum 25(OH)D levels were positively correlated with age (P = 0.019), whereas intact PTH levels were inversely correlated with 25(OH)D levels (P < 0.001). Thus, low vitamin D levels with high intact PTH levels were more common in younger than in older women. Our data show that serum 25(OH)D insufficiency could be a more serious concern in the younger population than had been previously anticipated. Because serum 25(OH)D insufficiency is reportedly a risk factor for hip and spine fracture, the number of fracture patients could increase in the future, suggesting that we may need to correct the serum vitamin D/intact PTH status to prevent future osteoporosis.
- 著者
- Koji Tamai Hidetomi Terai Akinobu Suzuki Hiroaki Nakamura Masaomi Yamashita Yawara Eguchi Shiro Imagama Kei Ando Kazuyoshi Kobayashi Morio Matsumoto Ken Ishii Tomohiro Hikata Shoji Seki Masaaki Aramomi Tetsuhiro Ishikawa Atsushi Kimura Hirokazu Inoue Gen Inoue Masayuki Miyagi Wataru Saito Kei Yamada Michio Hongo Kenji Endo Hidekazu Suzuki Atsushi Nakano Kazuyuki Watanabe Junichi Ohya Hirotaka Chikuda Yasuchika Aoki Masayuki Shimizu Toshimasa Futatsugi Keijiro Mukaiyama Masaichi Hasegawa Katsuhito Kiyasu Haku Iizuka Kotaro Nishida Kenichiro Kakutani Hideaki Nakajima Hideki Murakami Satoru Demura Satoshi Kato Katsuhito Yoshioka Takashi Namikawa Kei Watanabe Kazuyoshi Nakanishi Yukihiro Nakagawa Mitsunori Yoshimoto Hiroyasu Fujiwara Norihiro Nishida Masataka Sakane Masashi Yamazaki Takashi Kaito Takeo Furuya Sumihisa Orita Seiji Ohtori
- 出版者
- The Japanese Society for Spine Surgery and Related Research
- 雑誌
- Spine Surgery and Related Research (ISSN:2432261X)
- 巻号頁・発行日
- vol.1, no.4, pp.179-184, 2017-10-20 (Released:2017-11-27)
- 参考文献数
- 26
- 被引用文献数
- 3 3
Introduction: With an aging population, the proportion of patients aged ≥80 years requiring cervical surgery is increasing. Surgeons are concerned with the high incidence of complications in this population, because "age" itself has been reported as a strong risk factor for complications. However, it is still unknown which factors represent higher risk among these elderly patients. Therefore, this study was conducted to identify the risk factors related to surgical complications specific to elderly patients by analyzing the registry data of patients aged ≥80 years who underwent cervical surgery.Methods: We retrospectively studied multicenter collected registry data using multivariate analysis. Sixty-six patients aged ≥80 years who underwent cervical surgery and were followed up for more than one year were included in this study. Preoperative patient demographic data, including comorbidities and postoperative complications, were collected from multicenter registry data. Complications were considered as major if they required invasive intervention, caused prolonged morbidity, or resulted in prolongation of hospital stay. Logistic regression analysis was performed to analyze the risk factors for complications. A p-value of <0.05 was considered as statistically significant.Results: The total number of patients with complications was 21 (31.8%), with seven major (10.6%) and 14 minor (21.2%) complications. Multivariate logistic regression analysis, after adjusting for age, revealed two significant risk factors: preoperative cerebrovascular disorders (OR, 6.337; p=0.043) for overall complications and cancer history (OR, 8.168; p=0.021) for major complications. Age, presence of diabetes mellitus, and diagnosis were not significant predictive factors for complications in this study.Conclusions: Preoperative cerebrovascular disorders and cancer history were risk factors for complications after cervical surgery in patients over 80 years old. Surgeons should pay attention to these specific risk factors before performing cervical surgery in elderly patients.
- 著者
- Taku Suzuki Takuji Iwamoto Noboru Matsumura Masaya Nakamura Morio Matsumoto Kazuki Sato
- 出版者
- The Keio Journal of Medicine
- 雑誌
- The Keio Journal of Medicine (ISSN:00229717)
- 巻号頁・発行日
- pp.2019-0004-OA, (Released:2019-07-06)
- 参考文献数
- 20
- 被引用文献数
- 7
Percutaneous ultrasonic tendon needling has been used to treat persistent lateral epicondylitis, and its efficacy has been demonstrated. However, whether ultrasonography is necessary remains unclear. The purpose of this retrospective study was to evaluate the efficacy of percutaneous tendon needling without ultrasonography for lateral epicondylitis. A total of 36 patients who underwent tendon needling without ultrasonography for lateral epicondylitis were retrospectively included in the study. The tendinotic lesion was needled by fenestration approximately 20–30 times without sonographic assistance. The Visual Analogue Scale (VAS) pain score, the grip strength, and success rates were assessed at baseline and at 1, 3, 6, and 12 months after treatment. The Nirschl tennis elbow score was evaluated at baseline and at 6 and 12 months after the needling procedure. The mean VAS pain score and grip strength at 3, 6, and 12 months significantly improved compared to the baseline values. At 6 and 12 months, the success rates had significantly increased compared to the rates at 1 month. The mean Nirschl scores at 6 and 12 months were significantly better than the baseline value. No severe complications were observed during the study period. Percutaneous tendon needling without ultrasonography is a simple and safe technique. The procedure is effective for lateral epicondylitis that is unresponsive to conventional conservative treatments.