文献一覧: Hiroshi Yokomichi (著者)

3 0 0 0 OA Prevention Measures for COVID-19 and Changes in Kawasaki Disease Incidence

著者: Nobuyuki Katsumata Daisuke Harama Takako Toda Yuto Sunaga Masashi Yoshizawa Yosuke Kono Yohei Hasebe Keiichi Koizumi Minako Hoshiai Tomohiro Saito Sho Hokibara Koji Kobayashi Miwa Goto Tomoaki Sano Makoto Tsuruta Makoto Nakamura Sonoko Mizorogi Masanori Ohta Mie Mochizuki Hiroki Sato Hiroshi Yokomichi Takeshi Inukai
出版者: Japan Epidemiological Association
雑誌: Journal of Epidemiology (ISSN:09175040)
巻号頁・発行日: vol.31, no.11, pp.573-580, 2021-11-05 (Released:2021-11-05)
参考文献数: 42
被引用文献数: 6

Background: Kawasaki disease is suspected to be triggered by previous infection. The prevention measures for coronavirus disease 2019 (COVID-19) have reportedly reduced transmission of certain infectious diseases. Under these circumstances, the prevention measures for COVID-19 may reduce the incidence of Kawasaki disease.Methods: We conducted a retrospective study using registration datasets of patients with Kawasaki disease who were diagnosed in all 11 inpatient pediatric facilities in Yamanashi Prefecture. The eligible cases were 595 cases that were diagnosed before the COVID-19 pandemic (from January 2015 through February 2020) and 38 cases that were diagnosed during the COVID-19 pandemic (from March through November 2020). Incidence of several infectious disease were evaluated using data from the Infectious Disease Weekly Report conducted by the National Institute of Infectious Diseases.Results: Epidemics of various infectious diseases generally remained at low levels during the first 9 months (March through November 2020) of the COVID-19 pandemic. Moreover, the incidence of COVID-19 was 50–80 times lower than the incidence in European countries and the United States. The total number of 38 cases with Kawasaki disease for the 9 months during the COVID-19 pandemic was 46.3% (−3.5 standard deviations [SDs] of the average [82.0; SD, 12.7 cases] for the corresponding 9 months of the previous 5 years. None of the 38 cases was determined to be triggered by COVID-19 based on their medical histories and negative results of severe acute respiratory syndrome coronavirus 2 testing at admission.Conclusion: These observations provide a new epidemiological evidence for the notion that Kawasaki disease is triggered by major infectious diseases in children.

2022-12-03 21:05:50
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2 0 0 0 OA Mother’s iodine exposure and infants’ hypothyroidism: the Japan Environment and Children’s Study (JECS)

著者: Hiroshi Yokomichi Mie Mochizuki Reiji Kojima Sayaka Horiuchi Tadao Ooka Yuka Akiyama Kunio Miyake Megumi Kushima Sanae Otawa Ryoji Shinohara Zentaro Yamagata
出版者: The Japan Endocrine Society
雑誌: Endocrine Journal (ISSN:09188959)
巻号頁・発行日: vol.69, no.1, pp.9-21, 2022 (Released:2022-01-28)
参考文献数: 36
被引用文献数: 1 4

In this study, we aimed to determine the association of neonatal/post-neonatal hypothyroidism with mother’s iodine exposure, especially povidone iodine disinfection, and hysterosalpingography. Participants were mother–child pairs in a Japanese birth cohort (n = 100,286). Risk factors of hypothyroidism were supplement intake, seaweed intake, other daily iodine intake, povidone iodine disinfection at delivery, and maternal history of hysterosalpingography, thyroid disease (Graves’ disease and Hashimoto’s thyroiditis), and medication (thiamazole and levothyroxine). Congenital hypothyroidism (CH) at age 1 year was assessed using a questionnaire. Transient hypothyroidism was defined as elevated thyroid stimulating hormone level at birth and absence of CH at age 1 year. The incidence of CH at age 1 year per 100 children was 1.1 for those born at 22–30 weeks’ gestation, 0.17 following povidone iodine disinfection, and 0.07, 0.95, 0.81, 1.17, and 1.15 with a maternal history of hysterosalpingography, Graves’ disease, Hashimoto’s thyroiditis, thiamazole use, and levothyroxine use, respectively. Odds ratios (95% confidence intervals) of CH at age 1 year for povidone iodine disinfection, hysterosalpingography history, maternal Graves’ disease, and maternal Hashimoto’s thyroiditis were 1.13 (0.71–1.79), 0.47 (0.07–3.36), 7.06 (3.70–13.5), and 5.93 (2.90–12.1), respectively. For transient hypothyroidism for povidone iodine disinfection and hysterosalpingography history, these values were 1.99 (1.51–2.62) and 0.63 (0.20–1.96), respectively. Maternal thyroid disease greatly increased neonatal/post-neonatal hypothyroidism risk. Povidone iodine disinfection may increase transient hypothyroidism risk but not the risk at 1 year of age. Hysterosalpingography does not increase hypothyroidism risk from birth to age 1 year.

2023-10-18 21:47:47
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2 0 0 0 OA Relationship Between Socioeconomic Status and the Prevalence of Underweight, Overweight or Obesity in a General Japanese Population: NIPPON DATA2010

著者: Tomiyo Nakamura Yasuyuki Nakamura Shigeyuki Saitoh Tomonori Okamura Masahiko Yanagita Katsushi Yoshita Yoshikuni Kita Yoshitaka Murakami Hiroshi Yokomichi Nobuo Nishi Nagako Okuda Aya Kadota Takayoshi Ohkubo Hirotsugu Ueshima Akira Okayama Katsuyuki Miura
出版者: Japan Epidemiological Association
雑誌: Journal of Epidemiology (ISSN:09175040)
巻号頁・発行日: vol.28, no.Supplement_III, pp.S10-S16, 2018-03-05 (Released:2018-03-05)
参考文献数: 20
被引用文献数: 22

Background: Socioeconomic status (SES) imbalances in developed and developing countries may result in individuals being overweight and obese. However, few studies have investigated this issue in Japan. We herein examined the relationship between SES and being underweight, overweight or obese according to sex and age groups (20–64 or ≥65 years) in Japan.Methods: In 2010, we established a cohort of participants in the National Health and Nutrition Survey of Japan. We divided 2,491 participants (1,081 men and 1,410 women) according to the WHO definitions of underweight, overweight or obesity and performed multinomial logistic analyses using BMI <18.5 kg/m2 (underweight), BMI 25.0–29.9 kg/m2 (overweight), and BMI ≥30.0 kg/m2 (obese) versus BMI 18.5–24.9 kg/m2 (normal) as the outcome, with SES groups as the main explanatory variables.Results: In adult men, a lower education level relative to a higher education level was inversely associated with obesity after adjustments for other SESs (odds ratio [OR] 0.41; 95% confidence interval [CI], 0.18–0.96). However, in adult women, lower education level was positively associated with being overweight and obese (OR 1.67; 95% CI, 1.07–2.49 for overweight and OR 2.66; 95% CI, 1.01–7.01 for obese). In adult women, a lower household income was positively associated with being overweight and obese (obese: OR 4.84; 95% CI, 1.36–17.18 for those with a household income <2 million JPY relative to those with ≥6 million JPY).Conclusions: In adult women, a lower education level and lower household income were positively associated with being overweight or obese. In contrast, in adult men, a lower education level was inversely associated with obesity. Gender and age differences in SESs affect the prevalence of being overweight or obese.

2018-12-19 15:34:43
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2 0 0 0 OA Cholesterol levels of Japanese dyslipidaemic patients with various comorbidities: BioBank Japan

著者: Hiroshi Yokomichi Hokuto Noda Akiko Nagai Makoto Hirata Akiko Tamakoshi Yoichiro Kamatani Yutaka Kiyohara Koichi Matsuda Kaori Muto Toshiharu Ninomiya Michiaki Kubo Yusuke Nakamura BioBank Japan Cooperative Hospital Group Zentaro Yamagata
出版者: 日本疫学会
雑誌: Journal of Epidemiology (ISSN:09175040)
巻号頁・発行日: vol.27, no.Supplement_III, pp.S77-S83, 2017 (Released:2017-04-14)
参考文献数: 32
被引用文献数: 3

Background: Controlling serum cholesterol is critical to prevent cardiovascular disease in patients with dyslipidaemia. Guidelines emphasise the need to select treatment for dyslipidaemia based on specific patient profiles; however, there is little information about the serum cholesterol levels of patients in each profile in Japan. Therefore, we aimed to describe the serum cholesterol levels and prevalence of uncontrolled cases in Japanese patients with dyslipidaemia.Methods: We included data for patients with dyslipidaemia between 2003 and 2007 from the BioBank Japan Project (66 hospitals). Then, we reported their serum cholesterol levels by age, body mass index, glycaemic control (glycated haemoglobin A1c), blood pressure, smoking, drinking, comorbidity and medication profiles.Results: We included 22,189 male and 21,545 female patients. The mean serum low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglyceride (TG) and non-HDL-C levels in males were 117.4 mg/dL, 51.0 mg/dL, 187.6 mg/dL and 153.6 mg/dL, respectively; the corresponding levels in females were 129.5 mg/dL, 60.5 mg/dL, 144.9 mg/dL and 157.9 mg/dL, respectively. In both males and females, the LDL-C levels were the highest in the following profiles: age 19–44 years, body mass index 18.5–22 kg/m2, glycated haemoglobin A1c <6.0%, never smoker, chronic respiratory disease as a comorbidity and no medication use.Conclusions: These data provide details of serum cholesterol levels by risk-factor profile in patients with dyslipidaemia and could add evidence of treatment decisions.

2 0 0 0 OA Serum glucose, cholesterol and blood pressure levels in Japanese type 1 and 2 diabetic patients: BioBank Japan

著者: Hiroshi Yokomichi Akiko Nagai Makoto Hirata Yutaka Kiyohara Kaori Muto Toshiharu Ninomiya Koichi Matsuda Yoichiro Kamatani Akiko Tamakoshi Michiaki Kubo Yusuke Nakamura BioBank Japan Cooperative Hospital Group Zentaro Yamagata
出版者: 日本疫学会
雑誌: Journal of Epidemiology (ISSN:09175040)
巻号頁・発行日: vol.27, no.Supplement_III, pp.S92-S97, 2017 (Released:2017-04-14)
参考文献数: 28
被引用文献数: 12

Background: Evidence of characteristics of Japanese patients with diabetes from a large-scale population is necessary. Few studies have compared glycaemic controls, complications and comorbidities between type 1 and 2 diabetic patients. This paper focuses on illustrating a clinical picture of Japanese diabetic patients and comparing glycaemic control and prognoses between type 1 and 2 diabetes using multi-institutional data.Methods: The BioBank Japan Project enrolled adult type 1 and 2 diabetic patients between fiscal years 2003 and 2007. We have presented characteristics, controls of serum glucose, cholesterol and blood pressure, prevalence of complications and comorbidities and survival curves. We have also shown glycaemic controls according to various individual profiles of diabetic patients.Results: A total of 558 type 1 diabetic patients and 30,834 type 2 diabetic patients participated in this study. The mean glycated haemoglobin A1c was higher in type 1 diabetes than in type 2 diabetes. In the type 1 diabetic patients, the glycated haemoglobin A1c had no consistent trend according to age and body mass index. The Kaplan–Meier estimates represented a longer survival time from baseline with type 1 diabetes than with type 2 diabetes. Compared with type 1 diabetic patients, type 2 diabetic patients had double the prevalence of macrovascular complications.Conclusions: This work has revealed detailed plasma glucose levels of type 1 and 2 diabetic patients according to age, body mass index, blood pressure, serum cholesterol levels and smoking and drinking habits. Our data have also shown that the prognosis is worse for type 2 diabetes than for type 1 diabetes in Japan.

2 0 0 0 OA Survival of macrovascular disease, chronic kidney disease, chronic respiratory disease, cancer and smoking in patients with type 2 diabetes: BioBank Japan cohort

著者: Hiroshi Yokomichi Akiko Nagai Makoto Hirata Yutaka Kiyohara Kaori Muto Toshiharu Ninomiya Koichi Matsuda Yoichiro Kamatani Akiko Tamakoshi Michiaki Kubo Yusuke Nakamura BioBank Japan Cooperative Hospital Group Zentaro Yamagata
出版者: 日本疫学会
雑誌: Journal of Epidemiology (ISSN:09175040)
巻号頁・発行日: vol.27, no.Supplement_III, pp.S98-S106, 2017 (Released:2017-04-14)
参考文献数: 39
被引用文献数: 17

Background: The number of patients with diabetes is increasing worldwide. Macrovascular disease, chronic kidney disease, chronic respiratory disease, cancer and smoking frequently accompany type 2 diabetes. Few data are available related to mortality of Asians with diabetes associated with these serious comorbidities. The present study aimed to quantify the excess mortality risks of type 2 diabetic patients with comorbidities.Methods: We analysed the available records of 30,834 Japanese patients with type 2 diabetes from the BioBank Japan Project between 2003 and 2007. Men and women were followed up for median 8.03 and 8.30 years, respectively. We applied Cox proportional hazard model and Kaplan–Meier estimates for survival curves to evaluate mortality in diabetic patients with or without macrovascular disease, chronic respiratory disease, chronic kidney disease, cancer and smoking.Results: Adjusted hazard ratios (HRs) for mortality were 1.39 (95% CI, 1.09–1.78) for male sex, 2.01 (95% CI, 1.78–2.26) per 10-year increment of age. Adjusted HRs of primary interest were 1.77 (95% CI, 1.42–2.22), macrovascular disease; 1.58 (95% CI, 1.08–2.31), chronic respiratory disease; 2.03 (95% CI, 1.67–2.47), chronic kidney disease; 1.16 (95% CI, 0.86–1.56), cancer; and 1.74 (95% CI, 1.30–2.31), current smoking.Conclusions: Diabetic patients with a past or current history of chronic kidney, macrovascular or respiratory diseases or smoking habit have exhibited the highest risk of mortality. Data were limited to those of survivors of comorbidities but we propose the need to improve comorbidities and terminate cigarette smoking for better prognosis in patients with diabetes.

1 0 0 0 OA Infantile peanut introduction and peanut allergy in regions with a low prevalence of peanut allergy: the Japan Environment and Children’s Study (JECS)

著者: Reiji Kojima Ryoji Shinohara Megumi Kushima Hideki Yui Sanae Otawa Sayaka Horiuchi Kunio Miyake Hiroshi Yokomichi Yuka Akiyama Tadao Ooka Zentaro Yamagata the Japan Environment and Children’s Study Group
出版者: Japan Epidemiological Association
雑誌: Journal of Epidemiology (ISSN:09175040)
巻号頁・発行日: pp.JE20230210, (Released:2023-11-04)
参考文献数: 33

Background: In regions with a high prevalence of peanut allergy (PA), there is a consensus that the introduction of peanuts in early infancy is preventive against the development of PA. However, few studies have investigated whether the introduction of peanuts to infants is associated with PA in regions with a low prevalence of PA, including Japan.Methods: We used data from 74,240 mother–child pairs who participated in the Japan Environment and Children’s Study, a prospective birth cohort recruited between January 2011 and March 2014. A logistic regression model was used to analyze the association between infantile peanut introduction and PA at the age of 4 years with non-infantile peanut introduction as the reference group, adjusted for potential confounders.Results: The percentage of infantile peanut introduction was 4.9% (n=3294) and 286 (0.4%) participants had allergic symptoms to peanuts at 4 years of age. Of all participants, 129 (0.2%) had PA at 4 years of age, which was defined as allergic symptoms and sensitization to peanuts. Those with infantile peanut introduction had a lower prevalence of PA than those without infantile peanut introduction, although this did not reach statistical significance (adjusted odds ratio: 0.53, 95% confidence interval, 0.17–1.68). Sensitivity analysis using IgE-mediated symptoms caused by peanuts as the outcome showed a similar result in relation to infantile peanut introduction.Conclusions: In countries with a low prevalence of PA, the effect of infantile peanut introduction on PA prevention was unclear.

2023-11-07 15:02:02
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1 0 0 0 OA Effect of birth season on allergic rhinitis and cedar pollinosis considering allergen and vitamin D exposure: The Japan Environment and Children's study (JECS)

著者: Reiji Kojima Ryoji Shinohara Megumi Kushima Sayaka Horiuchi Sanae Otawa Kunio Miyake Hiroshi Yokomichi Yuka Akiyama Tadao Ooka Zentaro Yamagata the Japan Environment and Children's Study Group
出版者: Japanese Society of Allergology
雑誌: Allergology International (ISSN:13238930)
巻号頁・発行日: vol.72, no.3, pp.411-417, 2023 (Released:2023-07-07)
参考文献数: 36
被引用文献数: 1

Background: The relationship between the season of birth, allergen sensitization, and allergic rhinitis have been inconsistent, and there are no studies that simultaneously consider vitamin D and allergen exposure. This study aimed to determine the associations between the season of birth, house dust mite (HDM) and Japanese cedar pollen (JCP) sensitization, and allergic rhinitis and pollinosis, while taking vitamin D levels and allergen exposure into account.Methods: This study included 4323 participants in the Sub-Cohort Study of the Japan Environment and Children's Study. A logistic regression model was used to analyze the association between the season of birth and sensitization to JCP or HDM (judged by specific immunoglobulin E) at age 2 and allergic rhinitis or pollinosis at age 3, adjusted for HDM or JCP exposure and vitamin D levels with potential confounders.Results: Participants born in spring or summer were more likely to have pollinosis than were those born in winter (adjusted odds ratio [aOR]: 2.08, 95% confidence interval [CI]: 1.13-3.82 for spring; aOR: 1.89, 95% CI: 1.03-3.47 for summer). Participants born in summer were more likely to have HDM sensitization than were those born in winter (Der p 1, aOR: 1.53, 95% CI: 1.10-2.15; Der f 1, aOR: 1.44, 95% CI: 1.03-2.01). Exposure to JCP and HDM were associated with pollinosis and HDM sensitization, respectively.Conclusions: Spring and summer births were associated with the development of pollinosis, and summer birth was associated with HDM sensitization, even when vitamin D and allergen exposure were considered. Further studies on mechanisms other than vitamin D and allergen exposure are required.

2023-10-22 10:54:22
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1 0 0 0 OA Prevention Measures for COVID-19 and Changes in Kawasaki Disease Incidence

著者: Nobuyuki Katsumata Daisuke Harama Takako Toda Yuto Sunaga Masashi Yoshizawa Yosuke Kono Yohei Hasebe Keiichi Koizumi Minako Hoshiai Tomohiro Saito Sho Hokibara Koji Kobayashi Miwa Goto Tomoaki Sano Makoto Tsuruta Makoto Nakamura Sonoko Mizorogi Masanori Ohta Mie Mochizuki Hiroki Sato Hiroshi Yokomichi Takeshi Inukai
出版者: Japan Epidemiological Association
雑誌: Journal of Epidemiology (ISSN:09175040)
巻号頁・発行日: pp.JE20210132, (Released:2021-09-04)
参考文献数: 42
被引用文献数: 6

2021-10-10 18:31:41
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