- 著者
- Shirato Kunio KANAZAWA MASAHARU ISHIKAWA KEN NAKAJIMA TOSHIYUKI TAKISHIMA TAMOTSU
- 出版者
- 社団法人日本循環器学会
- 雑誌
- Japanese circulation journal (ISSN:00471828)
- 巻号頁・発行日
- vol.46, no.1, pp.113-123, 1982-01-20
- 被引用文献数
- 1
We studied the effect of the pericardium on the end-diastolic pressure-segment length (P-L) relation in volume loading (Experiment I) and in acute ischemia (Experiment II). Experiment I: In 6 open chest dogs, segment length of left and right ventricles were measured using ultrasonic crystals during blood infusion. Drawing end-diastolic pressure (P, on ordinate) against segment length (L, on abscissa), the P-L curve with pericardium positioned upward compared to that without pericardium. The slopes (b) of the exponential curve (P = ae^<bL>) with pericardium were steeper than those without pericardium in both ventricles. The difference between the slopes with and without pericardium was significantly larger in the right ventricle (RV, 0.30 ± 0. 10, mean ± SEM) than in the left ventricle (LV, 0.05 ± 0.02, p < 0.05). These results show that the pericardium inhibits the distensibility of the free wall more in RV than in LV, and enhances a mechanical coupling of both ventricles during volume overload. Experiment II: In 8 open chest dogs, segment lengths of ischemic and non-ischemic regions in LV were measured after left circumflex coronary occlusion. When the segment lengths and LV pressure became stable, a pericardiectomy was performed. After the pericardiectomy, whereas heart rate and LV systolic pressure did not change, end-diastolic segment length in the ischemic region further lengthened (12.0 0.2 to 12.5 0.2 mm, p < 0.01) and that in the non-ischemic region did not change despite the concomitant fall in LV end-diastolic pressure (EDP, 11.9 0.6 to 9.8 0.6 mmHg, p < 0.01). These results suggest that the pericardium alters the LV end-diastolic pressure-volume relation and is one of the factors contributing to an increase in LVEDP during acute ischemia.
- 著者
- Yamazaki Takeshi Ishikawa Ken-ichi Kuramashi Yoshinobu Ukawa Akira
- 出版者
- American Physical Society
- 雑誌
- Physical review D (ISSN:15507998)
- 巻号頁・発行日
- vol.86, no.7, pp.074514, 2012-10
- 被引用文献数
- 92
We calculate the binding energies for multinucleon bound states with the nuclear mass number less than or equal to 4 in 2+1 flavor QCD at the lattice spacing of a=0.09 fm employing a relatively heavy quark mass corresponding to mπ=0.51 GeV. To distinguish a bound state from attractive scattering states, we investigate the volume dependence of the energy shift between the ground state and the state of free nucleons by changing the spatial extent of the lattice from 2.9 to 5.8 fm. We conclude that 4He, 3He, deuteron and dineutron are bound at mπ=0.51 GeV. We compare their binding energies with those in our quenched studies and also with several previous investigations.