- 著者
- Mahbubur Rahman Satoshi Morita Tsuguya Fukui Junichi Sakamoto
- 出版者
- 日本疫学会
- 雑誌
- Journal of Epidemiology (ISSN:09175040)
- 巻号頁・発行日
- vol.15, no.2, pp.38-40, 2005 (Released:2005-05-10)
- 参考文献数
- 4
- 被引用文献数
- 4 5
BACKGROUND: Physicians' perception and attitudes towards a research topic and trial management could influence their participation in a randomized controlled trial. The objectives of this study were to determine the reasons for physicians' participation in and attitudes towards the Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) trial.METHODS: CASE-J's main objective is to compare the effectiveness of an angiotensin II receptor antagonist (candesartan cilexetil) with that of a calcium channel blocker (amlodipine besilate) in terms of the incidence of cardiovascular events among high-risk hypertensive patients. We conducted a questionnaire survey among the physicians (n=512) participating in that trial to determine the reasons behind their participation and to elicit their reactions to the trial management.RESULTS: Eighty-eight percent of the 512 participating physicians responded to our survey. The main reasons for participation were clear objectives of the trial (85.1%), a simple protocol (61.1%), interest in finding out the inhibiting effects of the drugs on cardiac events (80.2%), and a well-organized support system (59.8%). As for negative factors, case registration and follow-up were considered cumbersome by 28.6% and 10.8%, respectively while 44.2% stated that support by the clinical research coordinators provided by the trial management authority was necessary for case screening, recruitment process, patient registration, and follow-up. Multivariate logistic regression analysis showed that participants who did not use a computer very regularly (odds ratio = 1.9, 95% confidence interval = 1.1-3.6) were more likely to consider the case registration and follow-up procedures as a cumbersome.CONCLUSION: The information generated by this study could be useful in designing future randomized controlled trials in Japan and abroad.J Epidemiol2005;15:38-40.
- 著者
- Tsutomu Matsumoto Junichi Sakamoto Manami Suzuki Dai Watanabe Naoki Yoshida
- 出版者
- Information Processing Society of Japan
- 雑誌
- Journal of Information Processing (ISSN:18826652)
- 巻号頁・発行日
- vol.31, pp.700-707, 2023 (Released:2023-09-15)
- 参考文献数
- 25
The RAM encryption encrypts the data on memory to prevent data leakage from an adversary to eavesdrop the memory space of the target program. The well-known implementation is Intel SGX, whose RAM encryption mechanism is definitely hardware dependent. In contrast, Watanabe et al. proposed a fully software-based RAM encryption scheme (SBRES). In this paper, we developed the tools for embedding the SBRES in C source codes for its practical application. We applied the tools to the source codes of some cryptographic implementations in Mbed TLS and confirmed that the tools successfully embedded the SBRES functionality in the cryptographic implementations.
- 著者
- Ainur Baizhumanova Junichi Sakamoto
- 出版者
- The Japanese Society of Strategies for Cancer Research and Therapy
- 雑誌
- Annals of Cancer Research and Therapy (ISSN:13446835)
- 巻号頁・発行日
- vol.18, no.2, pp.65-68, 2010-11-26 (Released:2010-11-26)
- 参考文献数
- 9
- 被引用文献数
- 1
Cancer is the third leading cause of premature death in Kazakhstan. Every year more than thirty thousand Kazakhstani people are diagnosed with cancer. The present article was undertaken to provide base for the cancer control programs in Kazakhstan. The most common types of cancer are lung, skin, breast and stomach. These four cancers combined account for over 44% of new cases of cancer. Lung cancer is the most common cancer in men accounting for nearly a quarter of cancer cases in men. Breast cancer is by far the most common cancer in women accounting for 20%. Cancer remains mainly a disease of older Kazakhstanis. The largest proportion of cancer deaths for both men and women were from lung cancer mainly caused by smoking. Deaths from cancers of the lung, stomach, breast and esophagus together accounted for almost a half (46%) of all cancer deaths. With an estimated 186.7 new cases and 166.7 deaths in 2006, cancer remains an important public health problem in Kazakhstan. The incidence of lung cancer, and several other forms of cancer, could be reduced by improved tobacco control and healthy lifestyle.