- 著者
-
Kanae Su
Takao Kato
Mamoru Toyofuku
Takeshi Morimoto
Hidenori Yaku
Yasutaka Inuzuka
Yodo Tamaki
Neiko Ozasa
Erika Yamamoto
Yusuke Yoshikawa
Yasuyo Motohashi
Hiroki Watanabe
Takeshi Kitai
Ryoji Taniguchi
Moritake Iguchi
Masashi Kato
Kazuya Nagao
Takafumi Kawai
Akihiro Komasa
Ryusuke Nishikawa
Yuichi Kawase
Takashi Morinaga
Toshikazu Jinnai
Mitsunori Kawato
Yukihito Sato
Koichiro Kuwahara
Takashi Tamura
Takeshi Kimura
KCHF Registry Investigators
- 出版者
- The Japanese Circulation Society
- 雑誌
- Circulation Reports (ISSN:24340790)
- 巻号頁・発行日
- vol.1, no.11, pp.517-524, 2019-11-08 (Released:2019-11-08)
- 参考文献数
- 30
- 被引用文献数
-
17
Background:We sought to explore the effects of previous heart failure (HF) hospitalization on mortality in patients hospitalized for acute decompensated HF (ADHF) in a large Japanese contemporary observational database.Methods and Results:We prospectively enrolled consecutive patients with ADHF in 19 participating hospitals between October 2014 and March 2016. Of 4,056 patients, 1,442 patients (35.4%) had at least 1 previous HF hospitalization (previous hospitalization group), while 2,614 patients (64.5%) did not have a history of HF hospitalization (de novo hospitalization group). Patients with previous hospitalization were older and more often had comorbidities such as anemia, and renal failure than those without. The cumulative 1-year incidence of all-cause death was significantly higher in the previous hospitalization group than in the de novo hospitalization group (28% vs. 19%, P<0.001). After adjusting confounders, the excess risk of the previous hospitalization group relative to the de novo hospitalization group for all-cause death remained significant (HR, 1.28; 95% CI: 1.10–1.50, P=0.001). The excess risk was significant in patients without advanced age, anemia, or renal failure, but not significant in patients with these comorbidities, with significant interaction. Increase in the number of hospitalizations was associated with an increased risk for mortality.Conclusions:In a contemporary ADHF cohort in Japan, repeated hospitalization was associated with an increasing, higher risk for 1-year mortality.