- 著者
- KOKO SUGAWARA MASAMI HATORI YUJI NISHIYAMA KOJI TOMITA HIDEO KAMEI MASATAKA KONISHI TOSHIKAZU OKI
- 出版者
- JAPAN ANTIBIOTICS RESEARCH ASSOCIATION
- 雑誌
- The Journal of Antibiotics (ISSN:00218820)
- 巻号頁・発行日
- vol.43, no.1, pp.8-18, 1990-01-25 (Released:2006-04-19)
- 参考文献数
- 3
- 被引用文献数
- 54 65
Streptomyces hygroscopicus No. P247-71 (ATCC 53709) produced a novel antibiotic eponemycin which exhibited specific in vivo antitumor effect against B16 melanoma. Structural studies assigned (4S)-1, 2-epoxy-2-hydroxymethyl-4-(N-isooctanoyl-L-serylamino)-6-methylhept-6-ene-3-one to eponemycin which is unrelated to the known antitumor antibiotics.