- 著者
- Kei Gotot Takayuki Kawashima
- 出版者
- The Society of Synthetic Organic Chemistry, Japan
- 雑誌
- 有機合成化学協会誌 (ISSN:00379980)
- 巻号頁・発行日
- vol.63, no.11, pp.1157-1170, 2005-11-01 (Released:2009-11-13)
- 参考文献数
- 52
- 被引用文献数
- 6 6
Several kinds of bowl-type molecules were designed for regulation of the reactivities of the functional groups in their cavities, especially for kinetic stabilization of highly reactive species which have been difficult of access by conventional methods. The “peripheral steric protection” by these molecular cavities effectively prevents the bimolecular decomposition of the reactive species such as dimerization or self-condensation, and enabled the isolation of various species including a sulfenic acid, a selenenic acid, an S-nitrosothiol, and a Se-nitrososelenol, which have been known as important but elusive intermediates in biological reactions. Utilization of the molecular bowls as the ligands for transition metal complexes is also described.