- 著者
- Kiminao KOGISO Makoto NOGUCHI Kazuyoshi HATADA Naoki KIDA Naofumi HIRADE Kenji SUGIMOTO
- 出版者
- The Society of Instrument and Control Engineers
- 雑誌
- SICE Journal of Control, Measurement, and System Integration (ISSN:18824889)
- 巻号頁・発行日
- vol.3, no.4, pp.229-236, 2010 (Released:2011-11-18)
- 参考文献数
- 20
- 被引用文献数
- 1 1
This paper presents some experimental validation results of an already-proposed switching control method for simultaneous achievement of collision avoidance and tracking control for a vehicle in a non-cooperative situation. To validate the method, an experimental control system is made, in which the vehicle is a toy model car possible to remotely control via infrared ray and a camera is used to measure the vehicle's state. After presenting the constructed control system, the effectiveness of the method is investigated with the results obtained from the several control experiments.
- 著者
- Kazuhisa Sugimoto Takahisa Nishimura Koji Nomura Kenji Sugimoto Takashi Kuriki
- 出版者
- The Pharmaceutical Society of Japan
- 雑誌
- Chemical and Pharmaceutical Bulletin (ISSN:00092363)
- 巻号頁・発行日
- vol.51, no.7, pp.798-801, 2003 (Released:2003-07-01)
- 参考文献数
- 16
- 被引用文献数
- 103 110
The effects of 4-hydroxyphenyl α-glucopyranoside (α-arbutin) and 4-hydroxyphenyl β-glucopyranoside (arbutin) on the activity of tyrosinase from human malignant melanoma cells were examined. The inhibitory effect of α-arbutin on human tyrosinase was stronger than that of arbutin. The Ki value for α-arbutin was calculated to be 1/20 that for arbutin. We then synthesized arbutin-α-glycosides by the transglycosylation reaction of cyclomaltodextrin glucanotransferase using arbutin and starch, respectively, as acceptor and donor molecules. The structural analyses using 13C- and 1H-NMR proved that the transglycosylated products were 4-hydroxyphenyl β-maltoside (β-Ab-α-G1) and 4-hydroxyphenyl β-maltotrioside (β-Ab-α-G2). These arbutin-α-glycosides exhibited competitive type inhibition on human tyrosinase, and their Ki values were calculated to be 0.7 mM and 0.9 mM, respectively. These arbutin-α-glycosides posessed stronger inhibitory activity than arbutin, but less activity than α-arbutin. These results suggested that the α-glucosidic linkage of hydroquinone-glycosides plays an important role in the inhibitory effect on human tyrosinase.