著者

Kyoko Kanamaru Saki Hayashi Kensuke Kojima Tetsuo Kobayashi

出版者

日本マイコトキシン学会

雑誌

マイコトキシン (ISSN:02851466)

巻号頁・発行日

vol.65, no.1, pp.49-56, 2015-01-31 (Released:2015-04-22)

参考文献数

24

被引用文献数

1

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Reactive oxygen species (ROS) are high reactive compounds, which are produced on the process of oxygen consumption in aerobic organisms. ROS can be vanished by several enzymes, but excess of ROS cause damage on the organisms by the oxidation of DNA, proteins and lipids and so on. In this short review, you will see the general information about ROS (how and where ROS are produced and vanished), and then our resent reports, which show the involvement of His-Asp phosphorelay signal transductions into the control of ROS production in Aspergillus nidulans.

著者

小島 健介 Kensuke KOJIMA

雑誌

SIG-FPAI = SIG-FPAI

巻号頁・発行日

vol.B5, no.03, pp.57-62, 2018-03-07

著者

Hiroshi Ureshino Toshihiko Ando Kensuke Kojima Hidekazu Itamura Shunichi Jinnai Kazuko Doi Koichi Ohshima Kazuya Kurogi Masaharu Miyahara Shinya Kimura

出版者

一般社団法人 日本内科学会

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

vol.54, no.24, pp.3205-3208, 2015 (Released:2015-12-15)

参考文献数

25

被引用文献数

1 12

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Rituximab treatment may cause or exacerbate Kaposi's sarcoma (KS) in patients with human immunodeficiency virus (HIV)-associated multicentric Castleman's disease. Despite the widespread use of rituximab, rituximab-induced KS has not yet been reported in HIV-negative patients with diffuse large B cell lymphoma (DLBCL). We herein report a case of KS that developed after undergoing rituximab-containing chemotherapy in an HIV-negative patient with DLBCL. An 84-year-old man who received rituximab-containing chemotherapy for the treatment of DLBCL developed severe infection, and subsequently KS. Our observations indicate that serious infections under rituximab treatment may trigger KS. KS should therefore be considered when skin tumors appear in lymphoma patients receiving rituximab-containing chemotherapy.