- 著者
- Annisa Rahma Muhammad Miftahul Munir Khairurrijal Anton Prasetyo Veinardi Suendo Heni Rachmawati
- 出版者
- The Pharmaceutical Society of Japan
- 雑誌
- Biological and Pharmaceutical Bulletin (ISSN:09186158)
- 巻号頁・発行日
- vol.39, no.2, pp.163-173, 2016-02-01 (Released:2016-02-01)
- 参考文献数
- 45
- 被引用文献数
- 93 133
An electrospun fiber of polyvinyl(pyrrolidone) (PVP)–Tween 20 (T20) with curcumin as the encapsulated drug has been developed. A study of intermolecular interactions was performed using Raman spectroscopy, Fourier transform infrared (FT-IR), differential scanning calorimetry (DSC), and X-ray diffraction (XRD). The Raman and FT-IR studies showed that curcumin preferrably interacted with T20 and altered PVP chain packing, as supported by XRD and physical stability data. The hydroxyl stretching band in PVP shifted to a lower wavenumber with higher intenstity in the presence of curcumin and PVP, indicating that hydrogen bond formation is more intense in a curcumin or curcumin–T20 containing fiber. The thermal pattern of the fiber did not indicate phase separation. The conversion of curcumin into an amorphous state was confirmed by XRD analysis. An in vitro release study in phosphate buffer pH 6.8 showed that intermolecular interactions between each material influenced the drug release rate. However, low porosity was found to limit the hydrogen bond-mediated release.
- 著者
- Ferry Iskandar Erlandy Dwinanto Mikrajuddin Abdullah Khairurrijal Oki Muraza
- 出版者
- Hosokawa Powder Technology Foundation
- 雑誌
- KONA Powder and Particle Journal (ISSN:02884534)
- 巻号頁・発行日
- vol.33, pp.3-16, 2016 (Released:2016-02-28)
- 参考文献数
- 82
- 被引用文献数
- 5 34
Enhanced oil recovery (EOR) in the last several years has become an important factor in oil production due to the shortfall in high quality crude oil. Heavy oil as one of the unconventional hydrocarbons is still vastly abundant in nature and is hence frequently explored with EOR. The viscous characteristic of heavy oil necessitates further in-situ upgrading processes to be executed before extraction. An interesting upgrading method is through aquathermolysis under the addition of catalyst. This review focuses on presenting nanoparticle catalysts, such as nickel-, iron- and cobalt-based nanocatalyst. The explanation covers topics from synthesis methods and characterization up to the effect of reducing the viscosity of heavy oil. Lastly, concluding remarks and future perspectives are highlighted regarding the visibility and available approaches of developing nanofluids for EOR.