著者

Yoshito Homma Masashi Watanabe Koji Inoue Tomonori Moritaka

出版者

The Japanese Society of Internal Medicine

雑誌

Internal Medicine (ISSN:09182918)

巻号頁・発行日

vol.59, no.14, pp.1773-1775, 2020-07-15 (Released:2020-07-15)

参考文献数

12

被引用文献数

17 30

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The novel coronavirus disease-2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2, has spread worldwide from China. There are no case reports from Asia of COVID-19 with facial paralysis and olfactory disturbance. We herein report a case of COVID-19 pneumonia in a Japanese woman who showed facial nerve palsy and olfactory disturbance.

著者

Satoshi Matsuoka Hideharu Amano Kengo Nakajima Koji Inoue Tomohiro Kudoh Naoya Maruyama Kenjiro Taura Takeshi Iwashita Takahiro Katagiri Toshihiro Hanawa Toshio Endo

雑誌

研究報告ハイパフォーマンスコンピューティング(HPC) (ISSN:21888841)

巻号頁・発行日

vol.2016-HPC-155, no.32, pp.1-14, 2016-08-01

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Slowdown and inevitable end in exponential scaling of processor performance, the end of the so-called “Moore's Law”is predicted to occur around 2025-2030 timeframe. Because CMOS semiconductor voltage is also approaching its limits, this means that logic transistor power will become constant, and as a result, the system FLOPS will cease to improve, resulting in serious consequences for IT in general, especially supercomputing. Existing attempts to overcome the end of Moore 's law are rather limited in their future outlook or applicability. We claim that data-oriented parameters, such as bandwidth and capacity, or BYTES, are the new parameters that will allow continued performance gains for periods even after computing performance or FLOPS ceases to improve, due to continued advances in storage device technologies and optics, and manufacturing technologies including 3-D packaging. Such transition from FLOPS to BYTES will lead to disruptive changes in the overall systems from applications, algorithms, software to architecture, as to what parameter to optimize for, in order to achieve continued performance growth over time. We are launching a new set of research efforts to investigate and devise new technologies to enable such disruptive changes from FLOPS to BYTES in the Post-Moore era, focusing on HPC, where there is extreme sensitivity to performance, and expect the results to disseminate to the rest of IT.

著者

Kyoichiro Yazaki Masato Otsuka Shohei Kataoka Mitsuru Kahata Asako Kumagai Koji Inoue Hiroshi Koganei Kenji Enta Yasuhiro Ishii

出版者

日本循環器学会

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

pp.CJ-16-1261, (Released:2017-03-22)

参考文献数

17

被引用文献数

41

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Background:Quantitative flow ratio (QFR) is a newly developed image-based index for estimating fractional flow reserve (FFR).Methods and Results:We analyzed 151 coronary arteries with intermediate stenosis in 142 patients undergoing wire-based FFR measurement using dedicated software. Predefined contrast flow QFR, which was derived from 3-dimensional quantitative coronary angiography (3-D QCA) withThrombolysis in Myocardial Infarction (TIMI) frame counts, was compared with FFR as a reference. QFR had good correlation (r=0.80, P<0.0001) and agreement (mean difference: 0.01±0.05) with FFR. After applying the FFR cut-off ≤0.8, the overall accuracy rate of QFR ≤0.8 was 88.0%. On receiver operating characteristics analysis, the area under the curve was 0.93 for QFR. In contrast, 3-D QCA-derived anatomical indices had insufficient correlation with FFR and diagnostic performance compared with QFR.Conclusions:QFR had good correlation and agreement with FFR and high diagnostic performance in the evaluation of intermediate coronary stenosis, suggesting that QFR may be an alternative tool for estimating myocardial ischemia.