著者

Koji Ueda Takashi Nagai

出版者

Pesticide Science Society of Japan

雑誌

Journal of Pesticide Science (ISSN:1348589X)

巻号頁・発行日

vol.46, no.3, pp.267-273, 2021-08-20 (Released:2021-08-31)

参考文献数

28

被引用文献数

2

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We investigated the relative sensitivity of duckweed Lemna minor and six species of algae to seven herbicides, using an efficient high-throughput microplate-based toxicity assay. First, we assessed the sensitivity of L. minor to the seven herbicides, and then we compared its sensitivity to that of previously published data for six algal species based on EC50 values. For five herbicides, the most sensitive species differed: L. minor was most sensitive to cyclosulfamuron: Raphidocelis subcapitata was most sensitive to pretilachlor and esprocarb: Desmodesmus subspicatus was most sensitive to pyraclonil; and Navicula pelliculosa was most sensitive to pyrazoxyfen. Simetryn was evenly toxic to all species, whereas 2,4-D was evenly less toxic, with only small differences in species sensitivity. These results suggested that a single algal species cannot represent the sensitivity of the primary producer assemblage to a given herbicide. Therefore, to assess the ecological effects of herbicides, aquatic plant and multispecies algal toxicity data sets are essential.

著者

Yoshinori Okamoto Takao Tobe Koji Ueda Tatsuyuki Takada Nakao Kojima

出版者

The Japanese Society of Toxicology

雑誌

The Journal of Toxicological Sciences (ISSN:03881350)

巻号頁・発行日

vol.40, no.2, pp.235-242, 2015-04-01 (Released:2015-03-14)

参考文献数

22

被引用文献数

6 11

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Propolis, a natural product derived from plants by honeybees, is a mixture of several hundred chemicals, including flavonoids, coumaric acids, and caffeic acids, some of which show estrogen-like activity. In this study, the estrogenic activity of crude ethanolic extract of Brazilian propolis was determined using several in vitro and in vivo assays. Propolis was found to bind to human estrogen receptors (ERs). Furthermore, propolis induced the expression of estrogen-responsive genes in ER-positive MCF-7 and Ishikawa cells. These in vitro assays suggest that propolis exerts estrogenic activity; therefore, in vivo experiments were conducted using ovariectomized rats. Oral administration of propolis (55 or 550 mg/kg/day for 3 days) significantly increased uterine wet weight and luminal epithelium thickness in comparison with the corresponding values in the corn oil-treated control group. Moreover, propolis induced ductal cell proliferation in the mammary glands. These effects were completely inhibited by full ER antagonist ICI 182,780, confirming that the effects of propolis are mediated by the ER. Our data show that oral intake of propolis induces estrogenic activity in ER-expressing organs in vivo and suggest that Brazilian propolis is a useful dietary source of phytoestrogens and a promising treatment for postmenopausal symptoms.

著者

Tetsuya Tanizaki Koji Ueda Masahiko Wakai

出版者

The Institute of Electrical Engineers of Japan

雑誌

IEEJ Transactions on Industry Applications (ISSN:09136339)

巻号頁・発行日

vol.120, no.11, pp.1313-1320, 2000-11-01 (Released:2008-12-19)

参考文献数

14

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The fire detection is very important to prevent a secondary disaster and to save the assistance for safe driving in the master plan of ITS. At present, the fire detectors, which have a high sensitivity, are used in order to detect the fire in tunnels. It has problems such that the detection area is very narrow and sensor head is fouled by exhaust fumes. Compared with the fire detectors, image sensor is suitable to detect the fire, because it can cover two-dimensional wide space. We had attempted elsewhere the fire detection, which compares two histograms with various shades of gray level, by means of image processing. However, there remained problems about the influence of passing vehicle in the actual outdoors environment. The flame has characteristic such that its state is unstable and repeats growth and decay. A new approach toward the fire detection based on fluctuation of the flame has been described in this paper. Conventional fire detectors could detect only a phenomenon of the fire. However, proposal method could detect not only the flame but also its position. We conducted simulation and field tests to verify the accuracy of this method, and confirmed the effectiveness.