- 著者
- Tsubasa Suzuki Yasuhiko Ono Hidenori Maeda Yoshiki Tsujimoto Yugo Shobugawa Clyde Dapat Mohd Rohaizat Hassan Chihiro Yokota Hiroki Kondo Isolde C. Dapat Kousuke Saito Reiko Saito
- 出版者
- Tohoku University Medical Press
- 雑誌
- The Tohoku Journal of Experimental Medicine (ISSN:00408727)
- 巻号頁・発行日
- vol.232, no.2, pp.97-104, 2014 (Released:2014-02-15)
- 参考文献数
- 31
- 被引用文献数
- 8 8
Influenza vaccination is considered the single most important medical intervention for the prevention of influenza. The dose of trivalent influenza vaccine in children was increased almost double since 2011/12 season in Japan. We estimated the influenza vaccine effectiveness for children 1-11 years of age using rapid test kits in Isahaya City, involving 28,884 children-years, over two consecutive influenza seasons (2011/12 and 2012/13). Children were divided into two groups, vaccinated and unvaccinated, according to their vaccination record, which was obtained from an influenza registration program organized by the Isahaya Medical Association for all pediatric facilities in the city. There were 14,562 and 14,282 children aged from 1-11 years in the city in 2011 and 2012 respectively. In the 2011/12 season, the overall vaccine effectiveness in children from 1-11 years of age, against influenza A and B were 23% [95% confidence interval (CI): 14%-31%] and 20% [95% CI: 8%-31%], respectively. In the 2012/13 season, vaccine effectiveness against influenza A and B was 13% (95% CI: 4%-20%) and 9% (95% CI: −4%-21%), respectively. The vaccine effectiveness was estimated using the rapid diagnosis test kits. Age-stratified estimation showed that vaccine effectiveness was superior in younger children over both seasons and for both virus types. In conclusion, the trivalent influenza vaccine has a significant protective effect for children 1-11 years of age against influenza A and B infection in the 2011/12 season and against influenza A infection in the 2012/13 season in a community in Japan.
- 著者
- Yoshihiro Noguchi Ikuto Sugita Yuta Hayashi Aki Yoshida Anri Ueno Manami Ohtubo Hayato Katsuno Hiroki Esaki Kousuke Saito Tomoya Tachi Hitomi Teramachi
- 出版者
- Japanese Society of Drug Informatics
- 雑誌
- Iyakuhin Johogaku (ISSN:13451464)
- 巻号頁・発行日
- vol.19, no.3, pp.127-132, 2017 (Released:2017-12-27)
- 参考文献数
- 18
Objective: Gastrointestinal tract injury associated with non-steroidal anti-inflammatory drugs (NSAIDs) remains a clinically significant problem. Therefore, evaluate using the signal detection that is also used clinically and report attention concerning the assessment of known adverse drug events.Methods: In this study, we analyzed data on the serious adverse event gastrointestinal tract injury collected from 2004 to 2013 using Japanese Adverse Drug Event Report (JADER). The indicated drugs were classified into 12 NSAIDs based on COX selectivity.Results: In the usual analysis, several COX-1 selective NSAIDs were detected, but the signals of aspirin and the COX-2-selective NSAIDs etodolac and meloxicam associated with gastrointestinal tract injury were detected using ad hoc analysis.Conclusion: Since the signal value is calculated from the data obtained from the spontaneous reporting system, it is influenced by the clinical use situation at the time of investigation. Therefore, the signal value decreases if the risk, for which a countermeasure has been established, is high. This result does not indicate that COX-1 selective NSAIDs are pharmacologically less risk of gastrointestinal tract injury than COX-2 selective NSAIDs. There is a need to focus risk on emphasis on NSAIDs signal detected by ad hoc analysis.
- 著者
- Koryu Sato Naoki Kondo Chiyoe Murata Yugo Shobugawa Kousuke Saito Katsunori Kondo
- 出版者
- Japan Epidemiological Association
- 雑誌
- Journal of Epidemiology (ISSN:09175040)
- 巻号頁・発行日
- vol.32, no.9, pp.401-407, 2022-09-05 (Released:2022-09-05)
- 参考文献数
- 40
- 被引用文献数
- 5
Background: Increasing the coverage of vaccinations recommended by the World Health Organization in the older adult population is an urgent issue, especially in the context of avoiding co-epidemics during the current coronavirus disease 2019 crisis. The aim of this study was to examine factors associated with the quality of perceived patient–physician communication and whether this variable was associated with increased odds of vaccination.Methods: We used cross-sectional data from the Japan Gerontological Evaluation Study conducted from October 2016 to January 2017. The participants were 22,253 physically and cognitively independent individuals aged 65 or older living in 39 municipalities in Japan. Multilevel logit models were used to estimate the odds of vaccination.Results: Among the participants, 40.0% and 58.8% had received pneumococcal and influenza vaccinations as per the recommended schedule, respectively. People with low educational levels were more likely to have a family physician but rate their experience in asking questions lower than those with higher educational levels. Having a family physician and high rating for physicians’ listening attitude were positively associated with increased odds of pneumococcal and influenza vaccinations. High rating for patients’ questioning attitude and shared decision-making, compared to an ambiguous attitude toward medical decision-making, were positively associated with increased odds of pneumococcal vaccination.Conclusion: The results suggest that promotion of having a family physician, better patient–physician communication, and shared decision-making may encourage older adults to undergo recommended vaccinations.