- 著者
- HIROSHI IZUMI MAKOTO HAYAKARI YOSHIKAZU KONDO TSUNEMATSU TAKEMOTO
- 出版者
- Tohoku University Medical Press
- 雑誌
- The Tohoku Journal of Experimental Medicine (ISSN:00408727)
- 巻号頁・発行日
- vol.117, no.1, pp.101-102, 1975 (Released:2008-11-28)
- 参考文献数
- 12
Dopamine-β-hydroxylase was partially purified from bovine adrenal medulla and the effect of carnosine on the dopamine-β-hydroxylase activity was investigated. Carnosine significantly inhibited the enzyme activity at the concentrations higher than 0.5mM. According to the Lineweaver-Burk plots, the inhibition observed appeared to be a non-competitive type with the substrate, tyramine.