著者
Takuya E. KISHIMOTO James K. CHAMBERS Kouki MIYAMA Nguyen V. SON Mun Keong KOK Mizuho UNEYAMA Yasutsugu MIWA Hiroyuki NAKAYAMA Kazuyuki UCHIDA
出版者
JAPANESE SOCIETY OF VETERINARY SCIENCE
雑誌
Journal of Veterinary Medical Science (ISSN:09167250)
巻号頁・発行日
vol.80, no.10, pp.1511-1514, 2018 (Released:2018-10-10)
参考文献数
15
被引用文献数
1

A hard palate mass was surgically removed from an Australian green tree frog (Litoria caerulea) and examined pathologically. The tumor consisted of sheets of small cells arranged in a tubular structure and cords or rosettes with fibrovascular stroma. Immunohistochemically, neoplastic cells were diffusely positive for cytokeratin and neuron-specific enolase and partially positive for S-100 and doublecortin. These findings indicate that the tumor originated from the neuroectodermal tissue. Based on these findings, the tumor was classified as a neuromastoma (neuroepithelioma). Sensory cells located in the hard palate of the frog were considered to be the origin of the tumor. The frog died after going through 3 surgeries and experiencing difficulties closing its mouth.