著者

Nakajima Kenichi Nansai Keisuke Matsubae Kazuyo Nagasaka Tetsuya

出版者

The Iron and Steel Institute of Japan

雑誌

ISIJ International (ISSN:09151559)

巻号頁・発行日

vol.54, no.11, pp.2657-2662, 2014

被引用文献数

8

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Recently, sustainable management of resources has become an increasingly recognized issue. Accordingly, interest in understanding the relationship between natural resources consumption and the global product supply chain has also been increasing. Material flow analysis (MFA) is a useful tool for understanding resource consumption and material cycles in national economies. However, detailed MFA studies of the materials embedded in foreign trade flows are rare.<br>This study identified global trade flow of iron embedded in bilateral trade between 231 countries by multiplying the trade volume of the commodities in the BACI (Base pour l'Analyse du Commerce International) database and the iron content of each commodity. We focused on the cases of Japan, China, and United States, and estimated the mass of iron embedded in imports and export. The identified total flows of iron embedded in international trade were 1.15 × 10⁹ t-Fe with 35.2% of the flows concentrated in three countries, Japan, China and United States, which are major crude steel production countries.

著者

Terai Hidenobu Shimizu Masami Ino Hidekazu Yamaguchi Masato Uchiyama Katsuharu Oe Kotaro Nakajima Kenichi Taki Junichi Kawano Masaya Mabuchi Hiroshi

出版者

THE SOCIETY OF NUCLEAR MEDICINE INC

雑誌

Journal of Nuclear Medicine (ISSN:01)

巻号頁・発行日

vol.44, no.10, pp.1612-1617, 2003-10

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Left ventricular (LV) systolic function in hypertrophic cardiomyopathy (HCM) is usually normal. Late in the disease, however, LV systolic dysfunction and dilatation are recognized. Although abnormalities in cardiac sympathetic nerve activity in patients with HCM have been demonstrated using 123I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy, the changes of cardiac sympathetic nerve activity throughout the clinical course from typical to end-stage HCM are unclear. The objective of this study was to evaluate the relationship between abnormalities on 123I-MIBG myocardial scintigraphy and pathophysiologic changes in patients with HCM. Methods: We performed 123I-MIBG scintigraphy on 46 patients with HCM and 18 age-matched control subjects. The patients were categorized into 3 groups: 28 patients with normal LV systolic function (group A), 9 patients with LV systolic dysfunction (group B), and 9 patients with LV systolic dysfunction and dilatation (group C). With planar 123I-MIBG imaging, the heart-to-mediastinum ratio for early and delayed acquisitions and the washout rate were calculated. With SPECT, polar maps of the LV myocardium were divided into 20 segments. The regional uptake and washout rate were calculated from semiquantitative 20-segment bull's-eye analysis. Results: The early uptake was significantly lower in group C than in the control group (P < 0.01). The washout rate was progressively higher in group A, group B, and group C (P < 0.01). Reduced regional early uptake was found in 2.9 ± 3.4 (group A), 4.1 ± 4.7 (group B), and 7.4 ± 4.3 (group C) segments, respectively. In group C, regional early uptake was significantly reduced, predominantly in the interventricular septal wall, and regional washout rate was increased in the apex and lateral wall. Conclusion: These results suggest that cardiac sympathetic nerve abnormalities in patients with HCM may advance with development of LV systolic dysfunction and dilatation and that 123I-MIBG myocardial scintigraphy may be a useful tool for the evaluation of pathophysiologic changes in HCM.

著者

Nakajima Kenichi Yamasaki Yoshimitsu Kusuoka Hideo Izumi Tohru Kashiwagi Atsunori Kawamori Ryuzo Shimamoto Kazuaki Yamada Nobuhiro Nishimura Tsunehiko

出版者

Springer Berlin / Heidelberg

雑誌

European Journal of Nuclear Medicine and Molecular Imaging (ISSN:16197070)

巻号頁・発行日

vol.36, no.12, pp.2049-2057, 2009-12

被引用文献数

29

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Purpose Diabetic patients have a high risk for cardiovascular events. The role of myocardial perfusion imaging was investigated in asymptomatic diabetic patients to evaluate short-term prognosis in a Japanese population. Methods A total of 506 asymptomatic patients ≥50 years of age who had carotid artery maximum intima-media thickness ≥1.1 mm, urinary albumin excretion of ≥30 mg/g creatinine, with additional criteria of abdominal obesity, low HDL cholesterol, high triglyceride level, and hypertension were enrolled and followed up over a 3-year period. Gated SPECT with stress-rest protocol was performed and analyzed by summed defect scores and QGS software. One-year cardiovascular events were analyzed. Results Myocardial ischemia was observed in 17% of patients, and abnormal perfusion findings of ischemia and/or scar were observed in 32% of patients. By the end of the 1-year follow-up, 33 (6.5%) cardiovascular events occurred including 6 all-cause deaths. Patients with summed stress score (SSS) >8 had a higher incidence of either death or cardiovascular events. Event-free survival rates for SSS 0–3, 4–8, 9–13, and ≥14 were 0.96, 0.95, 0.82, and 0.76, respectively. Multivariate Cox regression analysis showed that significant variables were SSS, history of cerebrovascular accident, and electrocardiographic abnormality at rest. Conclusion The 1-year interim summary showed that cardiovascular events were significantly higher in patients with SPECT abnormality, although hard cardiac event rate was relatively low. Targeted treatment strategy is required for asymptomatic but potentially high-risk diabetic patients.