- 著者
-
Tetsuya Asakawa
Qingxian Cai
Jiayin Shen
Ying Zhang
Yongshuang Li
Peifen Chen
Wen Luo
Jiangguo Zhang
Jinfeng Zhou
Hui Zeng
Ruihui Weng
Feng Hu
Huiquan Feng
Jun Chen
Jie Huang
Xiaoyin Zhang
Yu Zhao
Liekui Fang
Rongqing Yang
Jia Huang
Fuxiang Wang
Yingxia Liu
Hongzhou Lu
- 出版者
- International Research and Cooperation Association for Bio & Socio-Sciences Advancement
- 雑誌
- BioScience Trends (ISSN:18817815)
- 巻号頁・発行日
- pp.2023.01039, (Released:2023-03-14)
- 参考文献数
- 278
- 被引用文献数
-
4
Over three years have passed since the COVID-19 pandemic started. The dangerousness and impact of COVID-19 should definitely not be ignored or underestimated. Other than the symptoms of acute infection, the long-term symptoms associated with SARS-CoV-2 infection, which are referred to here as "sequelae of long COVID (LC)", are also a conspicuous global public health concern. Although such sequelae were well-documented, the understanding of and insights regarding LC-related sequelae remain inadequate due to the limitations of previous studies (the follow-up, methodological flaws, heterogeneity among studies, etc.). Notably, robust evidence regarding diagnosis and treatment of certain LC sequelae remain insufficient and has been a stumbling block to better management of these patients. This awkward situation motivated us to conduct this review. Here, we comprehensively reviewed the updated information, particularly focusing on clinical issues. We attempt to provide the latest information regarding LC-related sequelae by systematically reviewing the involvement of main organ systems. We also propose paths for future exploration based on available knowledge and the authors' clinical experience. We believe that these take-home messages will be helpful to gain insights into LC and ultimately benefit clinical practice in treating LC-related sequelae.