著者

Kyu Kim Darae Kim Sang-Eun Lee In Jeong Cho Chi Young Shim Geu-Ru Hong Jong-Won Ha

出版者

The Japanese Circulation Society

雑誌

Circulation Journal (ISSN:13469843)

巻号頁・発行日

pp.CJ-18-0609, (Released:2018-12-15)

参考文献数

22

被引用文献数

12

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Background: Infective endocarditis (IE) in cancer patients is increasing, but because little is known about it in these patients, we analyzed patient characteristics and outcomes and compared these factors in IE patients with and without cancer. Methods and Results: This retrospective cohort study included 170 patients with IE newly diagnosed between January 2011 and December 2015. Among 170 patients, 30 (17.6%) had active cancer. The median age of IE patients with cancer was higher than that of non-cancer patients. Nosocomial IE was more common in cancer patients. Non-dental procedures, such as intravenous catheter insertion and invasive endoscopic or genitourinary procedures, were more frequently performed before IE developed in cancer patients. Staphylococcus was the most common pathogen in cancer patients, whereas Streptococcus was the most common in non-cancer patients. In-hospital mortality was significantly higher in cancer patients with IE (34.4% vs. 12.4%, P<0.001). IE was an important reason for discontinuing antitumor therapy and withholding additional aggressive treatment in nearly all deceased cancer patients. Conclusions: IE is common in cancer patients and is associated with poorer outcomes. Patients with IE and cancer have different clinical characteristics. Additional studies regarding antibiotic prophylaxis before non-dental invasive procedures in cancer patients are needed, as cancer patients are not considered to be at higher risk of IE.

著者

Na-Young Kim Seonhee Ahn GwangJin Kim Donghyok Kwon Young-Joon Park Sang-Eun Lee

出版者

Japan Epidemiological Association

雑誌

Journal of Epidemiology (ISSN:09175040)

巻号頁・発行日

pp.JE20230051, (Released:2023-07-15)

参考文献数

14

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Objectives: Most COVID-19 outbreaks in South Korea occurred through close contact in dense and closed indoor environments. However, a COVID-19 outbreak occurred in a group that camped together at an outdoor camping site in 2020, raising the need to observe precautions even when outdoors. We aimed to investigate the epidemiological characteristics and the risk factors for transmission for developing precautionary measures during outdoor activities.Methods: A study was conducted among 10 patients during the outbreak that occurred at a domestic camping site in July 2020. The demographic and epidemiological characteristics were obtained through an epidemiological investigation; the transmission risk was evaluated through additional site visits and CCTV analysis.Results: The incidence rate of this outbreak was 55.6%. No other common sources of exposure other than that within the campsite were identified; the outbreak possibly occurred due to transmission via close contact with infected people during mealtime and conversation throughout the camping period without implementation of adequate prevention and control measures.Conclusion: It is the first COVID-19 outbreak that occurred at an outdoor camping site in South Korea. COVID-19 can spread even when outdoors, prevention and control measures such as maintaining social distancing and wearing a mask should be observed when a large number of people gather outdoors. To ensure safe camping, facility managers should keep the cleaning and hygiene, and users should minimize the risk of infection by following the recommended precautions while staying in public spaces.