- 著者
- Yukina Tatsuta Yukie Tanaka Akari Ikeda Shigeru Matsukawa Hajime Katano Shu Taira
- 出版者
- 日本質量分析学会
- 雑誌
- Mass Spectrometry (ISSN:2187137X)
- 巻号頁・発行日
- vol.6, no.3, pp.S0069-S0069, 2017-09-08 (Released:2017-09-15)
- 参考文献数
- 7
- 被引用文献数
- 8
We compared two ionization methods, matrix assisted laser desorption/ionization (MALDI) and nanoparticle assisted laser desorption/ionization (Nano-PALDI) mass spectrometry (MS), for the analysis of amino acids derivatized with Py-Tag™ that consists pyrylium-based compound. Py-Tag is a useful stable derivatization reagent due to wide mass differences (using 13C as the sole stable labelling isotope). For Py-Tag labelled lysine, sensitive signals that showed less noise with a ten times higher sensitivity, showed a wider mass difference by Nano-PALDI MS compared to MALDI MS.