- 著者
- Eisuke Kume Yuya Okayama Mituru Sugiyama Hiroyuki Takahashi Tomoko Muto Michael F. Wempe Hiroshi Ikegami Shin Wakui
- 出版者
- The Japanese Society of Toxicology
- 雑誌
- Fundamental Toxicological Sciences (ISSN:2189115X)
- 巻号頁・発行日
- vol.10, no.3, pp.R1, 2023 (Released:2023-06-06)
Editor’s Announcement Quantitative morphometric analysis of vimentin filaments in Sertoli cells of rats after in utero DBP exposureEisuke Kume, Yuya Okayama, Mituru Sugiyama, Hiroyuki Takahashi, Tomoko Muto, Michael F. Wempe, Hiroshi Ikegami, Shin Wakui(Fundamental Toxicological Sciences, 4, 85-93, 2017) I have retracted the above paper as Editor-in-Chief of Fundamental Toxicological Sciences since I have serious concerns about it, primarily due to inappropriate authorship on a non-negligible scale.Since the possibility of inappropriate authorship in this paper was raised, I contacted the co-authors to confirm this point. I found out that several of them considered their listing as co-authors to be inappropriate. In addition, more than half of the co-authors agreed to the retraction of this paper.These facts raise concerns about the paper. From the standpoint of maintaining the integrity of the research community, I felt that such a paper should be retracted at once.Accordingly, I sent a summary of my concerns about this paper to the corresponding author, Dr. Shin Wakui. I also had an online interview with him to discuss this matter. I told Dr. Wakui that inappropriate authorship on a non-negligible scale is a serious problem that raises concerns about the paper.I prepared a draft of this Editor’s Announcement and sent it to Dr. Wakui for review prior to revision and release. Although he did not agree to the retraction, I have decided to take this action from the standpoint of maintaining the integrity of the research community.I coordinated my response to this issue with Dr. Toshiyuki Kaji, Editor-in-Chief of The Journal of Toxicological Sciences, a sister journal of Fundamental Toxicological Sciences.Akira Naganuma, Ph.D.Editor-in-ChiefFundamental Toxicological Sciences
- 著者
- Eisuke Kume Yuya Okayama Mituru Sugiyama Hiroyuki Takahashi Tomoko Muto Michael F. Wempe Hiroshi Ikegami Shin Wakui
- 出版者
- The Japanese Society of Toxicology
- 雑誌
- Fundamental Toxicological Sciences (ISSN:2189115X)
- 巻号頁・発行日
- vol.4, no.2, pp.85-93, 2017-05-13 (Released:2017-05-13)
- 参考文献数
- 18
- 被引用文献数
- 1 1
This article was retracted. See the Notification.
- 著者
- Masaya Motohashi Michael F. Wempe Tomoko Mutou Yuya Okayama Norio Kansaku Hiroyuki Takahashi Masahiro Ikegami Masao Asari Shin Wakui
- 出版者
- The Japanese Society of Toxicology
- 雑誌
- The Journal of Toxicological Sciences (ISSN:03881350)
- 巻号頁・発行日
- vol.48, no.6, pp.R1, 2023 (Released:2023-06-06)
Editor’s AnnouncementIn utero-exposed di(n-butyl) phthalate induce dose dependent, age-related changes of morphology and testosterone-biosynthesis enzymes/associated proteins of Leydig cell mitochondria in ratsMasaya Motohashi, Michael F. Wempe, Tomoko Mutou, Yuya Okayama, Norio Kansaku, Hiroyuki Takahashi, Masahiro Ikegami, Masao Asari, Shin Wakui(The Journal of Toxicological Sciences, 41, 195-206, 2016) I have retracted the above paper as Editor-in-Chief of The Journal of Toxicological Sciences since I have serious concerns about it, primarily due to inappropriate authorship on a non-negligible scale.When it was brought to my attention that there was inappropriate authorship in this paper, I contacted the co-authors to confirm this point. I found out that the majority of them considered their listing as co-authors to be inappropriate. In addition, the majority agreed to the retraction of this paper.These facts raise concerns about the paper. From the standpoint of maintaining the integrity of the research community, I felt that such a paper should be retracted at once.Accordingly, I sent a summary of my concerns about the paper to the corresponding author, Dr. Shin Wakui. I also had an online interview with him to discuss this matter. I told Dr. Wakui that inappropriate authorship on a non-negligible scale is a serious problem that raises concerns about the paper.I prepared a draft of this Editor’s Announcement and sent it to Dr. Wakui for review prior to revision and release. Although he did not agree to the retraction, I have decided to take this action from the standpoint of maintaining the integrity of the research community.I coordinated my response to this issue with Dr. Akira Naganuma, Editor-in-Chief of Fundamental Toxicological Sciences, a sister journal of The Journal of Toxicological Sciences. Toshiyuki Kaji, Ph.D.Editor-in-ChiefThe Journal of Toxicological Sciences
- 著者
- Masaya Motohashi Michael F. Wempe Tomoko Mutou Yuya Okayama Norio Kansaku Hiroyuki Takahashi Masahiro Ikegami Masao Asari Shin Wakui
- 出版者
- The Japanese Society of Toxicology
- 雑誌
- The Journal of Toxicological Sciences (ISSN:03881350)
- 巻号頁・発行日
- vol.41, no.2, pp.195-206, 2016-04-01 (Released:2016-03-10)
- 参考文献数
- 36
- 被引用文献数
- 14 16
This article was retracted. See the Notification.
- 著者
- Norio Kansaku Shin Wakui Tomohiro Sasanami Takeshi Ohkubo
- 出版者
- Japan Poultry Science Association
- 雑誌
- The Journal of Poultry Science (ISSN:13467395)
- 巻号頁・発行日
- pp.0220023, (Released:2022-06-25)
- 被引用文献数
- 2
Difference of onset of increase of PRL content in the anterior pituitary gland and plasma PRL concentration during the late stage of chicken embryogenesis is well known. To investigate the disagreement, changes in PRL content and PRL mRNA levels, and the effects of vasoactive intestinal polypeptides (VIP) on PRL release and PRL mRNA expression were examined using western blot analysis and real-time PCR quantification. Changes in SPRL content were strongly correlated with PRL mRNA levels. The increase in PRL content on day 17 of incubation may be caused by the increase in PRL mRNA levels on day 16 of incubation. Additionally, the effects of VIP on PRL release from the embryonic anterior pituitary gland were not observed until day 18 of embryogenesis. These results suggest that increased levels of PRL mRNA and PRL content in the anterior pituitary gland are closely correlated. However, the increased expression of PRL mRNA observed on day 17 and the initiation of PRL release from the anterior pituitary gland on day 19 were differentially regulated. According to the results of western blot analysis, the proportion of glycosylated PRL (G-PRL) and non-glycosylated PRL (NG-PRL) in the anterior pituitary gland at the end stage of development differed from the proportion of PRL released from the anterior pituitary gland. According to the results of two-dimensional western blot analysis, no isoforms with different isoelectric points were detected in the culture medium on days 19 and 20. These data suggest that the peptide chains of G-PRL and NG-PRL were not modified. In conclusion, the differentiation of PRL-producing cells and the maturation of the hypothalamus and anterior pituitary gland were completed at the end stage of incubation, and that different factors regulated the initiation of PRL mRNA expression before day 18 of incubation.