著者
Yusuke SUZUKI Makoto HAYASHI Takuya YASUKAWA Hiroshi KOBAYASHI Kosuke MAKINO Yoriyuki HIRANO Shozo TAKAGI Laurence C. CHOW Bunnai OGISO
出版者
日本歯科理工学会
雑誌
Dental Materials Journal (ISSN:02874547)
巻号頁・発行日
pp.2014-255, (Released:2015-02-25)
参考文献数
31
被引用文献数
5

Aim of this study was to develop a novel fluorapatite-forming calcium phosphate cement (FA-CPC) with tricalcium silicate (TCS) for endodontic applications and to examine its in vitro and in vivo characteristics. The FA-CPC powder consisted of 62.8% CaHPO4, 30.8% CaCO3, and 6.4% NaF. One part of TCS was combined with 9 parts of FA-CPC powder (FA-CPC with TCS). A 1.5 M phosphate solution was used as cement liquid. Setting time (ST), diametral tensile strength (DTS), phase composition by X-ray diffraction (XRD), and cement alkalinity were analyzed. Cement biocompatibility was assessed using rat subcutaneous model. Cement ST was 10.3±0.6 min and DTS was 3.89±0.76 MPa. XRD patterns showed that highly crystalline apatitic material was the only significant phase present and pH value was approximate 11.0. FA-CPC with TCS demonstrated similar biocompatibility as that of mineral trioxide aggregate control. These results suggest that FA-CPC with TCS may be useful for endodontic applications.