著者
Yasuaki Nakayama Yuto Tashiro Yusuke Suzuki Yu Kajiwara Hala Zeidan Mirei Kawagoe Yuki Yokota Takuya Sonoda Kanako Shimoura Masataka Tatsumi Kengo Nakai Yuichi Nishida Tsubasa Bito Soyoka Yoshimi Tomoki Aoyama
出版者
The Society of Physical Therapy Science
雑誌
Journal of Physical Therapy Science (ISSN:09155287)
巻号頁・発行日
vol.30, no.4, pp.630-635, 2018 (Released:2018-04-20)
参考文献数
40
被引用文献数
9

[Purpose] Few studies on the transverse arch (TA) in the forefoot have been conducted. The forefoot is where pains occur most frequently and is related to walking and balance; hence, paying attention to TA is vital. However, the relationship between TA and foot muscles has not been investigated. Therefore, this study aims to investigate muscles related to TA. [Subjects and Methods] Nineteen healthy young males were included. Measurements of their feet, excluding one foot with recent foot pain (n=37), were obtained. The height of TA (TAH) was measured in two ways: during 10% and 90% loading of body weight. The cross-sectional area and thickness of five muscles were measured: flexor digitorum longus, peroneus longus and brevis, flexor hallucis brevis, flexor digitorum brevis (FDB) and abductor hallucis (ABH). All measurements were performed with an ultrasound device. [Results] FDB and ABH were correlated with TAH during 10% and 90% loading after removing the effect of body mass index and age. The greater FDB and ABH, the higher TAH. [Conclusion] As FDB becomes larger, the second, third and fourth metatarsal heads are raised more. Furthermore, the height of the first metatarsal head is lowered by a larger ABH. These mechanisms may increase TAH.
著者
Yoshihito Nihei Monami Kishi Hitoshi Suzuki Ayako Koizumi Maiko Yoshida Sho Hamaguchi Masako Iwasaki Hiromitsu Fukuda Hisatsugu Takahara Masao Kihara Shigeki Tomita Yusuke Suzuki
出版者
The Japanese Society of Internal Medicine
雑誌
Internal Medicine (ISSN:09182918)
巻号頁・発行日
vol.61, no.7, pp.1033-1037, 2022-04-01 (Released:2022-04-01)
参考文献数
19
被引用文献数
15

A 28-year-old woman experienced gross hematuria after the administration of the second dose of an messenger ribonucleic acid (mRNA) vaccine (BNT162b2). She was diagnosed with Immunogloblin A nephropathy (IgAN) by a renal biopsy two weeks after vaccination, which revealed a mild increase in mesangial cells and a matrix with co-depositions of galactose-deficient IgA1 and C3 in the mesangial region. The gross hematuria and proteinuria gradually improved without any medication, suggesting that immune activation by the mRNA vaccine may not elicit continuous disease progression of IgAN. Thus, further studies investigating the relationship between mRNA vaccines against COVID-19 and the progression of IgAN should be conducted.
著者
Risako HATADA Hidemi ISHIBASHI Yukiko SUWA Yusuke SUZUKI Natsumi HOKANISHI Atsushi YASUDA
出版者
Japan Association of Mineralogical Sciences
雑誌
Journal of Mineralogical and Petrological Sciences (ISSN:13456296)
巻号頁・発行日
pp.190724, (Released:2020-06-26)
被引用文献数
1

We conducted textural and chemical analyses of melt inclusions and their host plagioclase crystals in the scoria of the Izu–Omuroyama monogenetic volcano, erupted at ~ 4 ka in the Higashi–Izu monogenetic volcanic field, Japan. The groundmass melt was andesitic with ~ 59–61 wt% SiO2, and it contained abundant microphenocrysts of olivine and plagioclase. In contrast, ~ 59% of the plagioclase–hosted melt inclusions have rhyolitic compositions with ~ 70–75 wt% SiO2. The host plagioclase phenocrysts have cores with An# of 44.7 ± 4.2 [An# = 100Ca/(Ca + Na) in mol] and rims with An# of 68–78, and the calcic rims have compositions similar to the microphenocrysts. The cores of the host plagioclase phenocrysts have FeO* and K2O contents that are in equilibrium with the rhyolitic melt inclusions. Using the plagioclase–melt geohygrometers and assuming temperatures of 790–850 °C, we estimated the H2O contents of the rhyolitic melt inclusions to be ~ 4.4–10.2 wt%, indicating H2O–saturation depths of >4.5 km. Our results suggest that an inhibited reservoir of plagioclase–bearing rhyolitic melt existed beneath the monogenetic volcano at the time of the scoria eruption, which was ~ 800 years earlier than the first rhyolitic eruption in the volcanic field. Plagioclase content in the silicic reservoir is estimated to be less than 35.8%, suggesting the magma was eruptible. Our results demonstrate the potential usefulness of plagioclase–hosted melt inclusions for indicating the existence of such an inhibited silicic magma.
著者
Yoshihito Nihei Monami Kishi Hitoshi Suzuki Ayako Koizumi Maiko Yoshida Sho Hamaguchi Masako Iwasaki Hiromitsu Fukuda Hisatsugu Takahara Masao Kihara Shigeki Tomita Yusuke Suzuki
出版者
The Japanese Society of Internal Medicine
雑誌
Internal Medicine (ISSN:09182918)
巻号頁・発行日
pp.8787-21, (Released:2022-02-01)
参考文献数
19
被引用文献数
15

A 28-year-old woman experienced gross hematuria after the administration of the second dose of an mRNA vaccine (BNT162b2). She was diagnosed with IgA nephropathy (IgAN) by a renal biopsy two weeks after vaccination, which revealed a mild increase in mesangial cells and a matrix with co-depositions of galactose-deficient IgA1 and C3 in the mesangial region. The gross hematuria and proteinuria gradually improved without any medication, suggesting that immune activation by the mRNA vaccine may not elicit continuous disease progression of IgAN. Thus, further studies investigating the relationship between mRNA vaccines against COVID-19 and the progression of IgAN should be conducted.
著者
Yuto Tashiro Yuichi Nishida Ayaka Yamaoka Yusuke Suzuki Takayoshi Horii Hiroaki Arai Yutaka Yamaguchi Naoya Wada Isao Yokota Tomoki Aoyama
出版者
Japanese Association of Occupational Therapists
雑誌
Asian Journal of Occupational Therapy (ISSN:13473476)
巻号頁・発行日
vol.16, no.1, pp.87-93, 2020 (Released:2020-12-15)
参考文献数
31

Objectives: There are only a few functional evaluations that non-medical personnel can perform and interpret without guidance. Here, we have created a questionnaire that focused on eating activities, which can be used to evaluate motor function easily because most people could relate to eating activities. This study aimed to verify the reliability and validity of the developed questionnaire by comparing it with clinical evaluations for upper extremity function.Methods: This was a cross-sectional study. Patients who have cerebrovascular disease history with disabilities in the upper limb were included in the study. The questionnaire on eating activities was answered by the patients themselves. Upper extremity function was evaluated with the Fugl-Meyer Assessment (FMA). Work efficiency was evaluated with the General Aptitude Test Battery. Reliability of the questionnaire was assessed by test-retest reliability. Validity was evaluated using a correlation analysis.Results: The study included 16 participants. The results indicated that all items had sufficient reliability. The correlation between the questionnaire score of the hand and the FMA score of the wrist, hand, and arm was statistically significant.Conclusions: The developed questionnaire was reliable and significantly related to clinical evaluation of upper extremity functions. This questionnaire is of great value to patients with stroke to understand their functions.
著者
Takeshi NAKAMURA Makoto HAYASHI Muneaki TAMURA Masahiro KAKETANI Tomoka ITO Toshiki TAKAMIZAWA Yusuke SUZUKI Takuya YASUKAWA Akiyoshi SUGAWARA Osamu TAKEICHI
出版者
The Japanese Society for Dental Materials and Devices
雑誌
Dental Materials Journal (ISSN:02874547)
巻号頁・発行日
pp.2022-250, (Released:2023-03-18)
参考文献数
32

The recently developed biphasic calcium phosphate cement (BCPC) consists of α-tricalcium phosphate-tetracalcium phosphate as the solid phase and calcium phosphate solution as the liquid phase. BCPC powder is composed of a single solid solution with a monomodal size distribution. Here, we used a bacterial leakage model to examine the utility of BCPC as a seal for root-end filling. We prepared large (median particle size=9.96 µm; BCPC-L) and small (median particle size=4.84 µm; BCPC-S) BCPC powders. In total, 45 single-rooted teeth were instrumented, resected at the root-end, and retrofilled with experimental materials. Mineral trioxide aggregate (MTA) was used as the control. After visual confirmation of BCPC powder size and retrofilling quality by microscopy, bacterial leakage tests were conducted using Enterococcus faecalis. The bacterial leakage tests did not reveal any significant differences between BCPC-S and MTA. Our findings suggest that BCPC-S is useful for root-end filling.
著者
Yusuke SUZUKI Takane IMADA
出版者
THE JAPAN SOCIETY FOR AERONAUTICAL AND SPACE SCIENCES
雑誌
TRANSACTIONS OF THE JAPAN SOCIETY FOR AERONAUTICAL AND SPACE SCIENCES, AEROSPACE TECHNOLOGY JAPAN (ISSN:18840485)
巻号頁・発行日
vol.12, no.ists29, pp.Tg_11-Tg_19, 2014 (Released:2014-12-26)

Japan contributes essential services to space experiments and enables human activities included as part of the international partnership of the ISS program by utilizing the HTVs (Kounotori). As the next step toword on-orbit service, JAXA has commenced technical research into cargo return from orbit. The HTV was used in research as the base design and a return vehicle was added to enhance performance. The combined vehicle is called the "HTV-R". HTV-R enables JAXA to recover various samples of experiments conducted on the ISS and equips a new return vehicle called as "HRV (HTV Return Vehicle)" for the enhanced function. The HRV will fly autonomously and conduct lifting re-entry into the atmosphere by controlling the attitude and trajectory to a predefined splashdown point. Now two types of vehicle concepts are being investigated. One uses an HTV as the base system for orbital flight and minimizes the initial cost of HTV-R program, and the other integrates the HTV components into a new vehicle, optimizing the on-orbit functions to minimize the recurring cost.
著者
Kengo Nakai Hala Zeidan Yusuke Suzuki Yuu Kajiwara Kanako Shimoura Masataka Tatsumi Yuichi Nishida Tsubasa Bitoh Soyoka Yoshimi Tomoki Aoyama
出版者
The Society of Physical Therapy Science
雑誌
Journal of Physical Therapy Science (ISSN:09155287)
巻号頁・発行日
vol.31, no.2, pp.202-205, 2019 (Released:2019-02-07)
参考文献数
25
被引用文献数
6

[Purpose] Hallux valgus occurs in the forefoot where the transverse arch is located and may be a factor involved in forefoot pain. The relationship between forefoot pain and forefoot structure is unknown. This study aimed to analyze the relationship between forefoot pain and the transverse arch in patients with hallux valgus. [Participants and Methods] In this study, 122 (197 feet) adult females (46 to 86 years old) with hallux valgus were studied. By using questionnaires, the females were divided into two groups depending on whether or not they had forefoot pain (a group with forefoot pain [P group] and a group without forefoot pain [NP group]). The hallux valgus angle was measured using a goniometer, and the transverse arch was measured using a weight-bearing plantar ultrasonography imaging device. The transverse arch measurements included the transverse arch height and length. [Results] Only the transverse arch length, even after adjustment, was significantly greater in the P group. No significant difference was found between the hallux valgus angle and the transverse arch height. [Conclusion] The greater transverse arch length in the P group was possibly due to the collapsing transverse arch support muscles. Increased width probably caused inadequate impact absorption which in turn led to forefoot pain.
著者
Yoshinori Sasai Yusuke Suzuki Yoshimasa Takeuchi
出版者
Nihon University School of Dentistry
雑誌
Journal of Oral Science (ISSN:13434934)
巻号頁・発行日
vol.61, no.3, pp.481-482, 2019 (Released:2019-08-28)
参考文献数
3
被引用文献数
5

The social security system, including the national health insurance system, in Japan has been maintained at a world-class level since 1974. However, an increase in the number of elderly people, and a decrease in the working generation, caused by a declining birthrate, represents a serious issue for the system both in the present and future. This report analyzes the key problems in the current insurance system and also considers how they can be handled in the future.
著者
Yusuke Suzuki Atsushi Kouzuma Kazuya Watanabe
出版者
Applied Microbiology, Molecular and Cellular Biosciences Research Foundation
雑誌
The Journal of General and Applied Microbiology (ISSN:00221260)
巻号頁・発行日
pp.2019.04.007, (Released:2019-08-23)
参考文献数
26
被引用文献数
6

Here, we developed an all-in-one, broad host-range CRISPR/Cas9 vector system widely applicable to genome editing of proteobacteria. Plasmid pBBR1-Cas9 was constructed by cloning the cas9 gene from Streptococcus pyogenes into the broad host-range plasmid pBBR1MCS-2. We evaluated its applicability for frameshift mutagenesis of Shewanella oneidensis MR-1. Significant cell death was observed when MR-1 cells were transformed with a pBBR1-Cas9 derivative that expressed a single-guide RNA targeting the crp gene. However, cell death was partially prevented when a donor DNA fragment containing a modified crp sequence with a frameshift mutation was introduced using the same vector. All transformants (9 colonies) contained the expected frameshift mutation in their chromosomal crp genes. These results indicate that this vector system efficiently introduced CRISPR/Cas9-mediated double-strand DNA breaks and subsequent homology-directed repair. This work provides a simple and powerful genome-editing tool for proteobacteria that can harbor pBBR1-based plasmids.
著者
Tsubasa Bito Yuto Tashiro Yusuke Suzuki Mirei Kawagoe Takuya Sonoda Yasuaki Nakayama Yuki Yokota Tomoki Aoyama
出版者
The Society of Physical Therapy Science
雑誌
Journal of Physical Therapy Science (ISSN:09155287)
巻号頁・発行日
vol.30, no.8, pp.978-983, 2018 (Released:2018-07-24)
参考文献数
35
被引用文献数
4

[Purpose] The association between foot injuries and foot alignment, including the transverse arch height (TAH) and asymmetry, was examined in athletes participating in college track events. [Participants and Methods] This study included 55 male athletes participating in a college track and field club. Data including demographic information and the incidence of foot injuries within a year prior to participation in this study were obtained via questionnaires. TAH and the medial longitudinal arch height during 10 and 90% loading, leg-heel alignment, and the heel angle were measured before calculating the asymmetry of each alignment parameter measured. Participants were categorized into an injury or a normal group. Unpaired t-tests were used to perform between-group comparisons for each alignment parameter measured and asymmetry. Additionally, logistic regression analysis was performed to identify factors associated with foot injuries after adjustment for demographic data. [Results] TAH asymmetry during 10 and 90% loading was significantly greater in the injury group. Further logistic regression analysis performed showed that only TAH asymmetry during 90% loading was significantly associated with foot injuries after adjustment for demographic data. [Conclusion] With regard to track events, a greater asymmetry of forefoot TAH in a weight-bearing position was observed to be associated with foot injuries.
著者
Yuki Yokota Takuya Sonoda Yuto Tashiro Yusuke Suzuki Yu Kajiwara Hala Zeidan Yasuaki Nakayama Mirei Kawagoe Kanako Shimoura Masataka Tatsumi Kengo Nakai Yuichi Nishida Tsubasa Bito Soyoka Yoshimi Tomoki Aoyama
出版者
The Society of Physical Therapy Science
雑誌
Journal of Physical Therapy Science (ISSN:09155287)
巻号頁・発行日
vol.30, no.5, pp.719-725, 2018 (Released:2018-05-08)
参考文献数
52
被引用文献数
27

[Purpose] This study aimed to clarify the effects of Capacitive and Resistive electric transfer (CRet) on changes in muscle flexibility and lumbopelvic alignment after fatiguing exercise. [Subjects and Methods] Twenty-two healthy males were assigned into either the CRet (n=11) or control (n=11) group. Fatiguing exercise and CRet intervention were applied at the quadriceps muscle of the participants’ dominant legs. The Ely test, pelvic tilt, lumbar lordosis, and superficial temperature were measured before and after exercise and for 30 minutes after intervention. Statistical analysis was performed using one-way analysis of variance, with Tukey’s post-hoc multiple comparison test to clarify within-group changes and Student’s t-test to clarify between-group differences. [Results] The Ely test and pelvic tilt were significantly different in both groups after exercise, but there was no difference in the CRet group after intervention. Superficial temperature significantly increased in the CRet group for 30 minutes after intervention, in contrast to after the exercise and intervention in the control group. There was no significant between-group difference at any timepoint, except in superficial temperature. [Conclusion] CRet could effectively improve muscle flexibility and lumbopelvic alignment after fatiguing exercise.
著者
Takuya YASUKAWA Makoto HAYASHI Natsuko TANABE Hiromasa TSUDA Yusuke SUZUKI Takayuki KAWATO Naoto SUZUKI Masao MAENO Bunnai OGISO
出版者
日本歯科理工学会
雑誌
Dental Materials Journal (ISSN:02874547)
巻号頁・発行日
pp.2016-313, (Released:2017-02-22)
参考文献数
30
被引用文献数
9

Mineral trioxide aggregate (MTA) has excellent biocompatibility as well as bioactivity, including an ability to induce osteoblast differentiation. We examined the effects of the calcium-sensing receptor (CaSR) on osteogenic gene expression induced by MTA. MC3T3-E1 cells were cultured with or without (control) MTA. The expression levels of Runx2, type I collagen, and CaSR genes were analyzed by real-time polymerase chain reaction and their products were measured using enzyme-linked immunosorbent assays. The levels were increased significantly in cells exposed to MTA compared with control. Next, MC3T3-E1 cells were cultured with MTA and EGTA (a calcium chelator), because calcium ions were released continuously from MTA into the culture. Expression levels were decreased to control levels by MTA plus EGTA. NPS2143 (a CaSR antagonist) also reduced MTA-induced gene expression. These results suggest that MTA induced osteogenic gene expressions of Runx2 and type I collagen via CaSR in MC3T3-E1 cells.
著者
Yusuke SUZUKI Makoto HAYASHI Takuya YASUKAWA Hiroshi KOBAYASHI Kosuke MAKINO Yoriyuki HIRANO Shozo TAKAGI Laurence C. CHOW Bunnai OGISO
出版者
日本歯科理工学会
雑誌
Dental Materials Journal (ISSN:02874547)
巻号頁・発行日
pp.2014-255, (Released:2015-02-25)
参考文献数
31
被引用文献数
5

Aim of this study was to develop a novel fluorapatite-forming calcium phosphate cement (FA-CPC) with tricalcium silicate (TCS) for endodontic applications and to examine its in vitro and in vivo characteristics. The FA-CPC powder consisted of 62.8% CaHPO4, 30.8% CaCO3, and 6.4% NaF. One part of TCS was combined with 9 parts of FA-CPC powder (FA-CPC with TCS). A 1.5 M phosphate solution was used as cement liquid. Setting time (ST), diametral tensile strength (DTS), phase composition by X-ray diffraction (XRD), and cement alkalinity were analyzed. Cement biocompatibility was assessed using rat subcutaneous model. Cement ST was 10.3±0.6 min and DTS was 3.89±0.76 MPa. XRD patterns showed that highly crystalline apatitic material was the only significant phase present and pH value was approximate 11.0. FA-CPC with TCS demonstrated similar biocompatibility as that of mineral trioxide aggregate control. These results suggest that FA-CPC with TCS may be useful for endodontic applications.
著者
Masahiro Nishiyama Yusuke Suzuki Toshiyuki Katagi
出版者
日本農薬学会
雑誌
Journal of Pesticide Science (ISSN:1348589X)
巻号頁・発行日
vol.35, no.4, pp.447-455, 2010-11-25 (Released:2010-11-24)
参考文献数
20
被引用文献数
5 7

Metofluthrin [I, 2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl (EZ)-(1R,3R)-2,2-dimethyl-3-(prop-1-enyl)cyclopropanecarboxylate] was resistant to hydrolysis at pH 4 and 7 but moderately hydrolyzed with a half-life of 36.8 days at pH 9 and 25°C to form the corresponding acid and alcohol via ester cleavage. The activation energy was estimated to be 105 kJ mol−1 based on the hydrolysis rates at 25–50oC. By continuous exposure to light at >290 nm from a Xenon arc lamp at hydrolytically stable pH 4 and 25°C, I was rapidly photodegraded with half-lives of 1.1–3.4 days, mainly via ester cleavage and successive oxidation followed by mineralization to carbon dioxide. Spectroscopic analyses together with co-chromatography with authentic standards showed that the major degradates having an ester linkage were the aldehyde and carboxylic acid derivatives formed via oxidative cleavage of the prop-1-enyl group together with the diol formed possibly through an oxidative intermediate, such as an epoxide.