著者

Fumio WATANABE Shigeo TAKENAKA Hiromi KITTAKA-KATSURA Shuhei EBARA Emi MIYAMOTO

出版者

Center for Academic Publications Japan

雑誌

Journal of Nutritional Science and Vitaminology (ISSN:03014800)

巻号頁・発行日

vol.48, no.5, pp.325-331, 2002 (Released:2009-04-28)

参考文献数

35

被引用文献数

43 90 76

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Substantial amounts of vitamin B12 were found in some edible algae (green and purple layers) and algal health food (chlorella and spirulina tablets) using the Lactobacillus delbrueckii subsp. lactis ATCC7830 microbiological assay method. Corrinoidcompounds were purified and characterized from these algae to clarify the chemical properties and bioavailability of the algal vitamin B12. True vitamin B12 is the predominate cobamide of green and purple layers and chlorella tablets. Feeding the purple layer to vitamin B12-deficient rats significantly improved the vitamin B12 status. The results suggest that algal vitamin B12 is a bioavailable source for mammals. Pseudovitamin B12 (an inactive corrinoid) predominated in the spirulina tablets, which are not suitable for use as a vitamin B12 source, especially for vegetarians.