著者

Tomonori Watanabe Masahiro Nomura Kimiko Nakayasu Tomohito Kawano Susumu Ito Yutaka Nakaya

出版者

The University of Tokushima Faculty of Medicine

雑誌

The Journal of Medical Investigation (ISSN:13431420)

巻号頁・発行日

vol.53, no.1,2, pp.153-158, 2006 (Released:2006-03-11)

参考文献数

30

被引用文献数

11 12

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Background: The thermic effect of food (TEF) is higher in lean than in obese human subjects.Objective: Relationships between TEF and insulin resistance during meals, from the point of view of autonomic nervous activity, were evaluated.Methods: Autonomic nervous activity was evaluated in 20 young adults using the spectral analysis of heart rate variability from one hour before to two hours after a meal. Heart rate data were analyzed based on low frequency components (LF power, 0.04-0.15 Hz), high frequency components (HF power, 0.15-0.40 Hz), and LF/HF ratios. Energy expenditure and the TEF were measured 30 min after a meal. Homeostasis model of insulin resistance index (HOMA-IR) was also measured.Results: The LF/HF ratio was significantly increased 30 min after a meal (p<0.05). No correlation between LF power and HF power with TEF was found, but the LF/HF ratio was significantly and positively correlated with TEF (r=+0.56, p<0.05). Moreover, a significant negative correlation was found between the HOMA-IR and TEF (r=-0.601, p<0.05).Conclusions: The findings suggest that a reduction in insulin sensitivity induces a poor response of sympathetic nervous activity in the postprandial phase and a reduction in postprandial energy expenditure. J. Med. Invest. 53: 153-158, February, 2006

著者

伊藤 進 Susumu Ito

出版者

中京大学教養部

雑誌

中京大学教養論叢 (ISSN:02867982)

巻号頁・発行日

vol.38, no.3, pp.577-612, 1997