著者
MITSUAKI TSUNAKAWA OSAMU TENMYO KOJI TOMITA NOBUAKI NARUSE CHIKAKO KOTAKE TAKEO MIYAKI MASATAKA KONISHI TOSHIKAZU OKI
出版者
JAPAN ANTIBIOTICS RESEARCH ASSOCIATION
雑誌
The Journal of Antibiotics (ISSN:00218820)
巻号頁・発行日
vol.45, no.2, pp.180-188, 1992-02-25 (Released:2006-04-19)
参考文献数
14
被引用文献数
31 33

A strain of Amycolatopsis orientalis No. Q427-8 (ATCC 53884) was found to produce a complex of new antiviral antibiotics, quartromicin which consisted of at least six components A1, A2, A3, D1, D2 and D3. Structural studies suggested that they are a novel type of molecules unrelated to any known antibiotics. Each component of quartromicin exhibited antiviral activity against herpes simplex virus type 1, influenza virus type A and human immunodeficiency virus.