- 著者
- Yuji Hatano Hiroto Shimoyachi Tatsuya Asano Takahiro Kenmotsu Takuro Wada Yasuhisa Oya Hiroaki Nakamura Susumu Fujiwara
- 出版者
- Japan Society for Simulation Technology
- 雑誌
- 日本シミュレーション学会英文誌 (ISSN:21885303)
- 巻号頁・発行日
- vol.9, no.1, pp.198-205, 2022 (Released:2022-06-17)
- 参考文献数
- 12
- 被引用文献数
- 1
The goal of this study is to establish a simple experimental system to examine the rate of double strand breaks (DSBs) of genome-sized DNA molecules under irradiation of β-rays from tritium under well-controlled conditions for the validation of computer simulation on interactions of biomolecules and ionizing radiation. Irradiation effects were insignificant at tritium concentration of 1300 Bq/cm3, indicating that the effects of β-rays were far smaller than those of oxidation and/or thermal motion at the low dose rate (4.3 μGy/h). Clear increase in DSB rate was observed at tritium concentrations of 3.0—4.0 MBq/cm3. The temperature dependence of DSB rate was examined by using the high concentration tritiated water.
- 著者
- Yudai Watanabe Rikiya Shirato Takuro Wada Kousuke Iba Tomoko Sonoda Toshihiko Yamashita
- 出版者
- The Society of Physical Therapy Science
- 雑誌
- Journal of Physical Therapy Science (ISSN:09155287)
- 巻号頁・発行日
- vol.32, no.11, pp.748-753, 2020 (Released:2020-11-11)
- 参考文献数
- 30
- 被引用文献数
- 3
[Purpose] Isolated finger flexion associated with function of the flexor digitorum superficialis has been qualitatively assessed using standard and modified tests. The purpose of this study was to quantify isolated finger flexion in healthy participants. [Participants and Methods] We assessed 100 volunteers (mean age: 44.6 years) without upper limb dysfunction using the standard and modified flexor digitorum superficialis tests. The sum of the isolated active flexion angles of the metacarpophalangeal and proximal interphalangeal joints of the test finger was also calculated, with the other three fingers held in an extended position with our original jig. [Results] The mean isolated flexion angles were, respectively, 152.4° and 154.8° for the right and left index fingers, 161.1° and 160.4° for the middle fingers, 160.6° and 158.2° for the ring fingers, 129.4° and 134.6° for the independent flexor digitorum superficialis function, 85.8° and 74.7° for the common flexor digitorum superficialis function, and 75.8° and 71.2° for absent flexor digitorum superficialis function in the small finger. The functional variations of the flexor digitorum superficialis of the small fingers showed symmetry in 65.0% of the fingers but asymmetry in 35.0%. [Conclusion] The data obtained in this study provide normal reference values for the examination of independent movement disorders of the fingers.
- 著者
- Susumu CHIBA Kazumi YONEKURA Michio NONAKA Tomihiro IMAI Hiroyuki MATUMOTO Takuro WADA
- 出版者
- 一般社団法人 日本内科学会
- 雑誌
- Internal Medicine (ISSN:09182918)
- 巻号頁・発行日
- vol.43, no.1, pp.79-81, 2004 (Released:2005-01-07)
- 参考文献数
- 8
- 被引用文献数
- 8 23
Juvenile muscular atrophy of the distal upper extremity (Hirayama disease) is a benign and non-progressive motor neuron disease. Application of a cervical collar is believed to prevent progression of symptoms in the early stages, but there is no effective therapy for the advanced disease. We found that tendon transfer improved the activities of daily living (ADL) of a patient with advanced Hirayama disease. An operative reconstruction can be valuable, even in patients with Hirayama disease who have developed impaired ADL due to extensive intrinsic hand muscle atrophy.