- 著者
- Teruo ITOH Atsuko KOJIMOTO Kazuyuki UCHIDA James CHAMBERS Hiroki SHII
- 出版者
- JAPANESE SOCIETY OF VETERINARY SCIENCE
- 雑誌
- Journal of Veterinary Medical Science (ISSN:09167250)
- 巻号頁・発行日
- pp.20-0281, (Released:2020-12-21)
- 被引用文献数
- 10
We evaluated the postsurgical outcomes of cutaneous or subcutaneous mast cell tumors (MCTs, n=25) in 23 dogs, resected with lateral surgical margins proportional to the widest tumor diameter, including at least one facial plane. The tumor diameter range was 0.3–2.6 cm (median: 0.9 cm), and all were histologically diagnosed as Kiupel’s low-grade MCT. Resection was histologically complete in 20, close (deep margin) in three, and incomplete (deep margin) in two. No dogs developed local recurrence at the site of initial surgery during follow-up of 161–2,219 days (median: 976 days). These results suggest that resection of low-grade, relatively small MCTs with surgical margins proportional to the tumor diameter is a practical procedure with high success rates.
- 著者
- Teruo ITOH Atsuko KOJIMOTO Kazuyuki UCHIDA James CHAMBERS Hiroki SHII
- 出版者
- 一般社団法人 日本獣医麻酔外科学会
- 雑誌
- 日本獣医麻酔外科学雑誌 (ISSN:21896623)
- 巻号頁・発行日
- vol.50, no.1+2, pp.15-17, 2019 (Released:2020-05-08)
- 参考文献数
- 13
12歳のミニチュアダックスフンドにおいて、卵巣子宮摘出中に膀胱三角から突出する腫瘤が認められた。突出部の生検により悪性神経節細胞腫と診断されたため、周囲の正常膀胱壁を含めた腫瘍領域の全層切除を実施した。切除した病巣は、追加で実施した免疫組織化学検査でも悪性神経節細胞腫と診断された。2回目の手術から35ヶ月経過した時点で再発転移は認められていない。
- 著者
- Naruki FUJIMOTO Yoshiki TANIGUCHI Hiroko SONODA Yasuyuki KANEKO Toshiyuki MATSUZAKI Teruo ITOH Takuya HIRAI Kazuyuki UCHIDA Masahiro IKEDA
- 出版者
- JAPANESE SOCIETY OF VETERINARY SCIENCE
- 雑誌
- Journal of Veterinary Medical Science (ISSN:09167250)
- 巻号頁・発行日
- pp.23-0278, (Released:2023-12-20)
Aquaporins (AQPs) are water channel proteins, and the expression of AQPs in carcinoma cells has received much attention over the last 15 years. In the veterinary field, however, little is known about the expression of AQPs. In the present study using immunohistochemistry, we examined the expression of AQP1, AQP3, and AQP5 in canine mammary gland carcinomas. The 27 samples comprised 10 grade I, 12 grade II, and 5 grade III samples (See Materials and Methods section for grade classification method). AQP1 was expressed in only 2 of the grade III carcinomas, and the expression was limited to spindle-shaped cells in the solid structure and on the outside of the solid mass. AQP3-positive cells were observed in 20 of 22 grade I and II samples. On the other hand, among grade III carcinomas, AQP3 was expressed only in spindle-shaped cells in 1 sample. AQP5 was expressed in all grade I and II carcinomas but not in the grade III tumors. In addition, enhanced expression of basolateral AQP3 and apical AQP5 was observed in lobular hyperplastic cells. These results suggest that the expression patterns of AQP3 and AQP5 can be of help for judging the grading of canine mammary tumors and that AQP1 is likely to be involved in metastasis. Moreover, AQP3 and AQP5 might be relevant to lactation in female dogs.
- 著者
- Teruo ITOH Kazumi NIBE Atsuko KOJIMOTO Mayumi MIKAWA Kazuhiro MIKAWA Kazuyuki UCHIDA Hiroki SHII
- 出版者
- 公益社団法人 日本獣医学会
- 雑誌
- Journal of Veterinary Medical Science (ISSN:09167250)
- 巻号頁・発行日
- vol.68, no.8, pp.869-871, 2006 (Released:2006-09-05)
- 参考文献数
- 9
- 被引用文献数
- 7 15 13
A 5-year-old female border collie presented with erythematous skin lesions at the axillae, groin, mucocutaneous junctions, and pinnae. Biopsy revealed lymphocytic interface dermatitis with hydropic degeneration of basal cells and keratinocyte apoptosis. Based on gross and histological features, diagnosis of erythema multiforme was made. The disease was resolved by treatment with azathioprine, prednisolone, and a hypoallergenic diet. Finally, the skin lesion was controlled without drug therapy but recurred easily every time commercial foods except the hypoallergenic diet were used, suggesting that food substances triggered this outbreak.