- 著者
- Haipeng Fu Yipeng Mu Xin Zhang
- 出版者
- The Institute of Electronics, Information and Communication Engineers
- 雑誌
- IEICE Electronics Express (ISSN:13492543)
- 巻号頁・発行日
- vol.19, no.14, pp.20220241, 2022-07-25 (Released:2022-07-25)
- 参考文献数
- 32
- 被引用文献数
- 2
A 2.58THz detector based on plasma-wave theory proposed by Dyakonov and Shur was designed and fabricated in 55nm standard CMOS process. Each detector consists of a filter patch antenna and a metal-oxide-semiconductor field-effect-transistor (MOSFET). We design a filter antenna to receive the terahertz signal, and the output of detector is extracted by a phase-locked amplifier. The antenna generates filtering function by adding two pairs of branches to the feeding lines. The frequency selection function of high spectral resolution detector proposed in this paper is mainly realized by filtering antenna. According to the test results and HFSS simulation results, the proposed filter antenna is feasible. The detector can achieve a room-temperature maximum responsivity (RV) of 67.2V/W. Our results show that CMOS terahertz detectors have potential applications in the imaging field.
- 著者
- Bao-qiu Li Xin Dong Shi-hong Fang Gui-qin Yang Ji-you Gao Jian-xin Zhang Fang-min Gu Hua Zhao
- 出版者
- The Japanese Society of Toxicology
- 雑誌
- The Journal of Toxicological Sciences (ISSN:03881350)
- 巻号頁・発行日
- vol.35, no.3, pp.279-286, 2010-06-01 (Released:2010-06-01)
- 参考文献数
- 23
Aim: Non-cell corynebacterium parvum product (NCPP) is a new preparation of corynebacterium parvum (CP), an immunomodulator that displays anticancer activities. It is prepared by nanotechnology and is intended to minimize the side effects of CP. The aim of the present study was to evaluate the immunogenicity and systemic toxicity of NCPP compared with CP in animals. Methods: 30 monkeys were randomly divided into 5 groups and given CP (3 mg/monkey), three doses of NCPP (9, 3, 1 mg/monkey) and 0.9% normal saline (NS, 4 ml/monkey) individually by intramuscular injection twice a week for 13 weeks. The immunogenicity and systemic toxicity of NCPP and CP were compared. Results: NCCP and CP caused histopathological changes in the liver, spleen and kidney, but pathologic changes in NCCP-treated groups were slighter than that in the CP group. Only 9 mg/monkey of NCPP caused the similar damage as the CP in intensity. Deposition of immune complexes in the glomerular basement membrane was observed only in the CP group. ELISA detection showed that the anti-CP antibody was at a high level, while the anti-NCPP antibody was at low level and disappeared during the recovery period. Conclusion: Our study has led to the view that NCPP is safer than CP.