- 著者
- OTOTAKA HIGASHI YOKO KIKUCHI
- 出版者
- Tohoku University Medical Press
- 雑誌
- The Tohoku Journal of Experimental Medicine (ISSN:00408727)
- 巻号頁・発行日
- vol.112, no.3, pp.271-278, 1974 (Released:2008-11-28)
- 参考文献数
- 18
- 被引用文献数
- 28 31
The hydrogen peroxide (H2O2)-induced platelet aggregation could be inhibited by vitamin E-nicotinate and less effectively by vitamin E-acetate. The adenosine diphosphate (ADP)-induced platelet aggregation could be slightly inhibited by vitamin E-nicotinate. The lipid peroxidation of platelet exposed to H2O2 could also be inhibited by vitamin E-nicotinate. The lipid peroxide formation associated with membrane disruption may be involved in the mechanism underlying the H2O2-induced platelet aggregation.