著者

Y-HTaguchi Akira Okamoto

雑誌

研究報告バイオ情報学(BIO)

巻号頁・発行日

vol.2012-BIO-28, no.16, pp.1-6, 2012-03-21

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Proteomic analysis is very useful procedure to understand the bacterial behavior changes with reaction to the external environment. This is because most of genomic information of bacteria is devoted to code enzyme to control metabolic networks inside the individual cell. In this paper, we have performed proteomic analysis of Streptococcus pyogenes, which is known to be a flesh-eating bacteria and can cause several human life-threatening diseases. Its proteome during growth phase is measured for four time points under two different incubation conditions; with and without shaking. The purpose of it is to understand adaptivity to oxidative stress. Principal component analysis is applied and turns out to be useful to depict biologically important proteins for both supernatant and cell components.