Medieval literary works popular in manuscript culture were not necessarily inherited by the print culture. Then which texts were chosen to be published by the first generation of printers in England? This paper offers a preliminary overview of the reception of medieval literature in England in the transitional period from manuscript to print by comparing the list of publications of William Caxton, England's first printer, and that of his follower Wynkyn de Worde. While Caxton's publishing style was largely influenced by the manuscript tradition and distinguished by his translation (especially from French prose romance), de Worde seems to have been more active than his master in not only expanding the market for religious works and romance (both prose and verse) but also cultivating a relationship with his contemporary authors.