著者

大城 淳一 国吉 孝夫 盛島 浩明 照喜名 重順 城間 健治 新垣 聰 東恩納 厚 新垣 民樹 浦崎 政仁 佐久川 廣 金城 福則 斎藤 厚 Ohshiro Junichi Kuniyoshi Takao Morishima Hiroaki Terukina Shigeyoshi Shiroma Kenji Arakaki Satoshi Higashionna Atsushi Arakaki Tamiki Urasaki Masahito Sakugawa Hiroshi Kinjo Fukunori Saito Atsushi 琉球大学医学部第一内科

出版者

琉球大学医学部

雑誌

琉球大学医学会雑誌 : 医学部紀要 = Ryukyu medical journal (ISSN:02891530)

巻号頁・発行日

vol.11, no.1, pp.28-34, 1989

---

Sulfasalazine and corticosteroids have been used for the treatment of ulcerative colitis. Recently, it is investigated to use metronidazole for treatment of ulcerative colitis. We tried to use metronidazole for three patients with ulcerative colitis , to whom neither sulfasalazine nor corticosteroids were effective. In case 1 the patient was 37-year-old female,to whom conticosteroids had been ineffective. After treatment by metronidazole together with corticosteroids, the symptoms were improved. In case 2 the patient was 74-year-old female, who had relapsed during treatment with sulfasalazine. Treatment with metronidazole alone resulted in the remission of disease. In case 3 the patient was 32-yearold female, to whom the treatment with sulfasalazine and corticosteroids enema had been ineffecitve. By use of metronidazole together with sulfasalazine, she had remission. It seems that metronidazole is useful for the treatment of ulcerative colitis, especially in patients who did not respond to other drugs.