著者

片岡 洋祐

出版者

日本レーザー歯学会

雑誌

日本レーザー歯学会誌 (ISSN:09177450)

巻号頁・発行日

vol.18, no.2, pp.93-96, 2007-10-01 (Released:2010-10-21)

参考文献数

24

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Low-reactive level laser therapy has been applied for pain relief and improvement of local circulation, and hasbeen popular in many clinical fields. The cellular mechanism, however, has not been fully clarified. Some basic researches indicated that laser suppresses neural activity by direct action on the nervous tissue, and affects membrane potential and the input membrane resistance of neurons. Using low-reactive level laser irradiation with a near-infrared diode laser (continuouswave; wavelength, 830 nm; power density, 1-5 W/cm2), we achieved inactivation of excitatory synaptic transmission in the central nervous system of rodents. In the study using cultured rat hippocampal neurons, the laser irradiation induced hyperpolarization of the membrane potential and reduction of input membrane resistance, suggesting that the laser suppressed synaptictransmission by opening potassium channels in the cells. The laser irradiation increased the content of adenosine triphosphate (ATP) in the tissue. Furthermore, laser-induced suppression of synaptic transmission was attenuated under application of anATP-sensitive potassium channel opener. These observations indicate that suppression of neural activity by low-reactive levellaser irradiation in a near-infrared wavelength is brought about by opening of ATP-sensitive potassium channels by the increasein intracellular ATP level. Recently, it was demonstrated that laser irradiation suppressed synaptic transmission morepotently in hippocampal slices at a low ATP content. This may contribute to the clinical phenomenon that more potent effectsof low-reactive level laser irradiation are often seen on tissue under pathological states than physiological states.

著者

角 保徳

出版者

日本レーザー歯学会

雑誌

日本レーザー歯学会誌 (ISSN:09177450)

巻号頁・発行日

vol.23, no.3, pp.137-141, 2012-12-01 (Released:2012-12-17)

参考文献数

7

被引用文献数

4 2

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Optical coherence tomography (OCT) is a new biomedical imaging modality which can generate high-resolution, cross-sectional images of microstructures in biological systems. One of the most attractive features of OCT is that it uses safe near-infrared light instead of hazardous ionizing radiation. Furthermore, resolution on the order of 10 micrometers can be obtained. The optical accessibility of clinically relevant structures in the oral cavity makes it a particularly attractive location for the application of OCT imaging techniques. Our National Center for Geriatrics and Gerontology has developed a new swept-source optical coherence tomography (SS-OCT) system through joint research with industry and the public sector. In this study, this new SS-OCT system was applied to cross-sectional imaging of dental caries, resin based composite restorations, periodontal disease, oral cancer and finished dentures. It is concluded that our new SS-OCT system is a promising new and useful alternative imaging technique which can safely provide much more definitive information on oral structures at far higher resolution than is possible by conventional clinical imaging methods. The National Center for Geriatrics and Gerontology received the world's first production unit of this new dental SS-OCT system.

著者

大城 貴史 大城 俊夫 佐々木 克己

出版者

日本レーザー歯学会

雑誌

日本レーザー歯学会誌 (ISSN:09177450)

巻号頁・発行日

vol.27, no.1, pp.27-31, 2016-04-01 (Released:2016-06-04)

参考文献数

15

被引用文献数

2 2

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Photoactivation, also known as photobiomodulation, is recognized as one effect of laser/tissue interactions. This phenomenon, which is induced by low-level laser irradiation, was reported by Mester in the late 1960s. The therapeutic method with photoactivation was defined as low-reactive level laser therapy (LLLT) by Ohshiro in 1988. Today, various clinical applications using LLLT have been reported in the field of wound healing, pain attenuation, musculoskeletal injuries and so on.This introductory review covers the fundamentals of laser/tissue interactions and the basic mechanism of photoactivation to provide a better understanding of LLLT for wound healing.

著者

竹口 あゆみ 冨士谷 盛興 長塚 由香 八谷 文貴 井上 和穂 岸本 崇史 林 建佑 掘江 卓 千田 彰

出版者

日本レーザー歯学会

雑誌

日本レーザー歯学会誌 (ISSN:09177450)

巻号頁・発行日

vol.28, no.2+3, pp.23-30, 2017-12-01 (Released:2018-02-15)

参考文献数

28

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With the ultimate aim of newly developing an optimal dentin bonding system to Er:YAG-lased dentin, the adhesion-promoting effects of priming with hydrophilic monomers on the bonding performance of the resin-modified glass-ionomer adhesive system (RMGI) to laser-affected dentin were investigated. It was revealed that priming with 4-MET and HEMA following acid-conditioning with 10% citric acid+2% ferric chloride solution might be very effective for improving the bond strength of RMGI to Er:YAG-lased dentin.This work was supported by JSPS KAKENHI Grant Number JP15K11138.

著者

久保 勝俊 杉田 好彦 前田 初彦

出版者

日本レーザー歯学会

雑誌

日本レーザー歯学会誌 (ISSN:09177450)

巻号頁・発行日

vol.20, no.3, pp.174-178, 2009-12-01 (Released:2012-04-17)

参考文献数

17

被引用文献数

2

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Since the laser was developed in 1960,its applying to optical communication and medical practice has been investigated well. There are many kinds of dental laser and more than twelve of them are used in Japan. High-energy lasers are useful in producing coagulation necrosis in target tissue with a subsequent reaction in the surrounding tissue. Various biostimulatory effects of low-energy laser irradiation have been reported that it acts on regeneration healing, fibroblast and chondral proliferation, collagen synthesis, nerve regeneration. It is used in odontotherapy for diseases of hard tissue and soft tissue, periodontitis and peri-implantitis. The usage rate of a dental laser is 30% of dental clinics in Japan and 60% of them use a laser with carbon dioxide gas. In this paper, we describe the carbon dioxide whether promote the wound healing or not. The laser is used for a lot of medical treatments now. Moreover, the laser is used for not only the treatment; its usage also has been increased for diagnosis and prevention of the disease. Especially, its research and development progress rapidly due to applying to the odontology for medical treatment.

著者

野村 正

出版者

日本レーザー歯学会

雑誌

日本レーザー歯学会誌 (ISSN:09177450)

巻号頁・発行日

vol.27, no.1, pp.21-26, 2016-04-01 (Released:2016-06-04)

参考文献数

12

被引用文献数

2

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Wound healing in the oral mucosa, which covers the whole area of the oral cavity, is generally fast and the residual scar is minimal. Mucosal wound healing proceeds in the same manner as a cutaneous wound through the same stages, including hemostasis, inflammation, proliferation, and remodeling of collagen matrix. It is well known that ideal wound healing should be achieved by primary closure. On the other hand, the secondary intention of wound results in scar contracture. From the perspective of wound healing, the thermal damage created by a CO2-laser or YAG laser should be taken into consideration. In this article, we describe the process of normal wound healing and residual scar contracture in both skin and oral mucosa. Furthermore, we present the factors of abnormal wound healing.

著者

吉田 憲司

出版者

日本レーザー歯学会

雑誌

日本レーザー歯学会誌 (ISSN:09177450)

巻号頁・発行日

vol.20, no.3, pp.120-123, 2009-12-01 (Released:2012-04-17)

参考文献数

19

被引用文献数

1

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Low level laser therapy (LLLT) is gaining popularity in a variety of clinical applications. The lasers used in dental applications for LLLT are such as the He–Ne laser, the semiconductor laser and others. Low level laser light is reported to alleviate pain and trigeminal nerve paresthesia, to accelerate wound healing, to have a positive effect on inflammatory processes, the prevention and treatment of radiotherapy-induced oral mucositis in oral cancer. However, the biochemical reactions by low level laser irradiation are not fully understood. This paper presents the efficacy of LLLT and cautions when applying clinical in use.