- 著者
- Tadashi KIHO Shigeyuki USUI Kazuyuki HIRANO Koichi AIZAWA Takahiro INAKUMA
- 出版者
- Japan Society for Bioscience, Biotechnology, and Agrochemistry
- 雑誌
- Bioscience, Biotechnology, and Biochemistry (ISSN:09168451)
- 巻号頁・発行日
- vol.68, no.1, pp.200-205, 2004 (Released:2004-01-24)
- 参考文献数
- 31
- 被引用文献数
- 70
A water-soluble and low-molecular-weight fraction (SB) was obtained from tomato paste. The effects of SB on the formation of advanced glycation end-products (AGE) in protein glycation were studied by the methods of specific fluorescence, ELISA and a Western blot analysis, using the anti-AGE antibody after incubating protein with sugar. The results suggest that SB had strong inhibitory activity, in comparison with aminoguanidine as a positive control, and that the inhibitory mechanism of SB differed from that of aminoguanidine to involve trapping of reactive dicarbonyl intermediates in the early stage of glycation. SB contained an antioxidant, rutin, which showed potent inhibitory activity. The results also suggest that rutin chiefly contributed to inhibiting the formation of AGE, and that other compounds in SB may also have been related to the activity.
言及状況
外部データベース (DOI)
Twitter (31 users, 125 posts, 0 favorites)
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/jJ66RwTbzf
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/GsDfbTtaIM
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/GrBUKiYS8e
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/yATjmooHuo
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/GsDfbTtaIM
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/4YxOGDRWMc
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/MqQeAfhEIB
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/GrBUKiYS8e
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/8nPuTU0fmZ
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/ryKUR8brSN
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/yATjmooHuo
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/RH26rskvOX
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/GsDfbTtaIM
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/aEvOXSUl8Z
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/7ggCeVH27S
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/m3WJJBldlf
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/FrhMNJ8a4K
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/F0c6XWTYak
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/jJ66RwTbzf
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/hEZgPlCM0E
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/CkhoXc8BX0
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/GrBUKiYS8e
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/8nPuTU0fmZ
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. http://t.co/k653z1fl1g
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/GsDfbTtaIM
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/XXgJOsVRP8
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/Oq9w2tWLiq
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/ryKUR8brSN
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/yATjmooHuo
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/MqQeAfhEIB
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/aEvOXSUl8Z
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/hEZgPlCM0E
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. http://t.co/HA7zPZnyhS
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/whrbFRafWi
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/GsDfbTtaIM
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/FrhMNJ8a4K
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/hEZgPlCM0E
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/F0c6XWTYak
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/CXvBoOCbRe
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/GsDfbTtaIM
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/FrhMNJ8a4K
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/yATjmooHuo
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/8nPuTU0fmZ
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/tSGYQl8xUs
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/g2bKYRYsdv
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/GrBUKiYS8e
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/7Ob23kz98M
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/aEvOXSUl8Z
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. http://t.co/sanrcQkwvl
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/XXgJOsVRP8
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/GsDfbTtaIM
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/91lRnQcIRp
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/SO5EPgPJbV
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/vl7OsR8nc3
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/91lRnQcIRp
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/zXYOk1xN4z
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/GsDfbTtaIM
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/PtxFu3CbuR
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/I5uJQwT2kq
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/hbhzRmC1bS
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/vl7OsR8nc3
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/lIPhg2NLiz
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/EumV2DPuVD
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/91lRnQcIRp
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/NjKN9voYJF
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/CXvBoOCbRe
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/q3MNeVHNnl
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/95tO0mEajm
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/91lRnQcIRp
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/wvBb842lOk
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/pSdI1RxmZV
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/PtxFu3CbuR
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/Svzswpuqmy
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/CXvBoOCbRe
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/NTajdXHh7q
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/PtxFu3CbuR
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/wvBb842lOk
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/91lRnQcIRp
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/I5uJQwT2kq
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/PtxFu3CbuR
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/wB5xaJNxXf
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/LbgaS2MRzG
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/ag6omazA8K
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/Svzswpuqmy
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/SO5EPgPJbV
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/vl7OsR8nc3
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/EumV2DPuVD
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/91lRnQcIRp
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/hbhzRmC1bS
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/GrBUKiHgJE
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/m3WJJBCOcN
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/A61vRa42qK
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/j1QUpeWzCw
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/GsDfbTKLAk
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/MqQeAf03k1
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/hEZgPlUmSc
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/vl7OsR8nc3
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/GrBUKiHgJE
AGE FACT: Tomatoes have been shown to inhibit the formation of glycation end products. https://t.co/91lRnQcIRp