著者
Kosuke NISHI Ai KONDO Takeaki OKAMOTO Hiroyuki NAKANO Miho DAIFUKU Sogo NISHIMOTO Kenji OCHI Terumi TAKAOKA Takuya SUGAHARA
出版者
Japan Society for Bioscience, Biotechnology, and Agrochemistry
雑誌
Bioscience, Biotechnology, and Biochemistry (ISSN:09168451)
巻号頁・発行日
vol.75, no.1, pp.40-46, 2011-01-23 (Released:2011-01-23)
参考文献数
23
被引用文献数
15

The water-soluble fraction of kale (Brassica oleracea L. var. acephala DC.) had immunoglobulin (Ig) production stimulating activity in human hybridoma HB4C5 cells and human peripheral blood lymphocytes. The biochemical and physical properties of the main active substance in kale were found to be a heat-stable protein with a molecular weight higher than 50 kDa. The Ig production-stimulating factors were assumed to act on the translational and/or secreting processes of Igs. This Ig production-stimulating effect was also observed in lymphocytes from the mesenteric lymph node and Peyer’s patches of mice that had been administered with the kale extract for 14 d. The partially purified kale extract was analyzed by LC-ESI-MS/MS, the result indicating ribulose-1,5-bisphosphate carboxylase/oxygenase (rubisco) as an active substance. Rubisco from spinach indeed exhibited Ig production-stimulating activity in HB4C5 cells. These findings provide another beneficial aspect of kale as a health-promoting foodstuff.

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@ChristosArgyrop @RadCentrism Don't forget the kale. https://t.co/CI2ZsHNioS
@coalface_au @nutrition_facts Thanks for the question! The study in the video above showed a kale extract increased antibody production for cultured cells https://t.co/F5y3ndJhPN though it fits w/ many studies that show fruit & veg consumption correlates w/ immune function: https://t.co/sFbOIr4mNR

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