著者
Sumiyo Yasukawa Eri Eguchi Keiki Ogino Akiko Tamakoshi Hiroyasu Iso
出版者
The Japanese Circulation Society
雑誌
Circulation Journal (ISSN:13469843)
巻号頁・発行日
vol.82, no.5, pp.1302-1308, 2018-04-25 (Released:2018-04-25)
参考文献数
43

Background:Nulliparity is associated with an excess risk of cardiovascular disease (CVD). “Ikigai”, subjective wellbeing in Japan, is associated with reduced risk of CVD. The impact of ikigai on the association between parity and the risk of CVD, however, has not been reported.Methods and Results:A total of 39,870 Japanese women aged 40–79 years without a history of CVD, cancer or insufficient information at baseline in 1988–1990, were enrolled and followed until the end of 2009. They were categorized into 7 groups according to parity number 0–≥6. Using Cox regression hazard modeling, the associations between parity and mortality from stroke, coronary artery disease, and total CVD were investigated. During the follow-up period, 2,121 total CVD deaths were documented. No association was observed between parity and stroke and CVD mortality in women with ikigai, but there was an association in those without ikigai. The multivariable hazard ratios of stroke and total CVD mortality for nulliparous women without ikigai vs. those with 1 child were 1.87 (95% CI: 1.15–3.05) and 1.46 (95% CI: 1.07–2.01), respectively, and that for stroke mortality in high parity women without ikigai was 1.56 (95% CI: 1.00–2.45).Conclusions:Nulliparous or high parity women without ikigai had higher mortality from stroke and/or total CVD, suggesting that ikigai attenuated the association between parity and CVD mortality in Japanese women.

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外部データベース (DOI)

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The relationship between Ikigai and CVD mortality. #Ikigai #CVD #mortality https://t.co/VFzcHCiheO
今日は大規模コホート班会議で勉強させていただいてます ”生きがい”の論文がCirc Jに出てたのは面白かったです 内容は別としていろんな指標ありますね Do you have ikigai in your life? この論… https://t.co/ZNKU41wbvm

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