- 著者
-
Suguru Yoshida
Takamitsu Hosoya
- 出版者
- (社)日本化学会
- 雑誌
- Chemistry Letters (ISSN:03667022)
- 巻号頁・発行日
- vol.44, no.11, pp.1450-1460, 2015-11-05 (Released:2015-11-05)
- 参考文献数
- 159
- 被引用文献数
-
173
1
Recent developments in aryne chemistry are reviewed with a particular focus on synthetic methods. This includes an overview of the precursors of arynes and their activators; the generation of arynes with functional groups and their ensuing reactivities; and the novel transformations achieved via aryne intermediates. These newly developed methods have enabled the synthesis of a variety of previously inaccessible aromatic compounds, allowing the construction of a diversity-enriched chemical library that will further facilitate future drug discoveries.